TAVALISSE Drug Insight

“TAVALISSE Market Size, Forecast, and Drug Insight – 2032” report provides comprehensive insights about TAVALISSE for Thrombocytopenia and Immune Thrombocytopenic Purpura in the seven major markets. A detailed picture of the TAVALISSE in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 –2032 is provided in this report along with a detailed description of the TAVALISSE. The report provides insights about TAVALISSE Mechanism of Action, dosage, and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the TAVALISSE market forecast analysis in the 7MM, SWOT, analysts’ views, comprehensive overview of market competitors, and a brief about other emerging therapies.

TAVALISSE Drug Summary

Fostamatinib disodium (also known as TAVALISSE; R-985788) is an orally-bioavailable investigational agent being developed by Rigel pharmaceuticals and approved for the treatment of patients suffering from persistent/chronic adult idiopathic thrombocytopenic purpura. The therapeutic candidate inhibits FcR-triggered, Syk-dependent cytoskeletal rearrangement during phagocytosis. As stated by Rigel Pharmaceuticals, fostamatinib has a unique TAVALISSE mechanism of action, blocking IgG receptor signaling in both macrophages and B cells via SYK kinase.

TAVALISSE is approved in the US and the EU to treat chronic immune thrombocytopenia (ITP) and the Ministry of Health, Labour and Welfare (MHLW) has granted manufacturing and marketing approval to Kissei for the oral spleen tyrosine kinase (SYK) inhibitor, TAVALISSE for chronic idiopathic thrombocytopenic purpura (chronic ITP) in December 2022.

Dosage

TAVALISSE is initiated at a dose of 100 mg taken orally twice daily. After a month, if platelet count has not increased to at least 50 × 109/L, the dose should be increased to 150 mg twice daily. The lowest dose of TAVALISSE should be used to achieve and maintain a platelet count of at least 50 × 109/L as necessary to reduce the risk of bleeding. TAVALISSE may be taken with or without food. In the case of a missed dose of TAVALISSE, patients should be instructed to take their next dose at its regularly scheduled time.

TAVALISSE Mechanism of Action

Fostamatinib is a tyrosine kinase inhibitor with demonstrated activity against spleen tyrosine kinase (SYK). The major metabolite of fostamatinib, R406, inhibits signal transduction of Fc-activating receptors and B-cell receptors. The fostamatinib metabolite R406 reduces antibody-mediated destruction of platelets.

TAVALISSE Market Forecast Report Scope

The TAVALISSE Market Forecast Report provides insights into:

• A comprehensive product overview including the TAVALISSE description, TAVALISSE Mechanism of Action, dosage and administration, research and development activities in thrombocytopenia and immune thrombocytopenic purpura.
• Elaborated details on TAVALISSE regulatory milestones and other development activities have been provided in this report.
• The report also highlights the TAVALISSE research and development activities in thrombocytopenia and immune thrombocytopenic purpura across the United States, Europe and Japan.
• The TAVALISSE Market Forecast Report also covers the patents information with expiry timeline around TAVALISSE.
• The report contains forecasted TAVALISSE Sales for thrombocytopenia and immune thrombocytopenic purpura till 2032.
• Comprehensive coverage of the late-stage emerging therapies for thrombocytopenia and immune thrombocytopenic purpura.
• The TAVALISSE Market Forecast Report also features the SWOT analysis with analyst views for TAVALISSE in thrombocytopenia and immune thrombocytopenic purpura

TAVALISSE Methodology

The TAVALISSE Market Forecast Report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight’s team of industry experts. Information and TAVALISSE Sales Data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

TAVALISSE Market Analytical Perspective by DelveInsight

• In-depth TAVALISSE Market Assessment

This report provides a detailed market assessment of TAVALISSE for thrombocytopenia and immune thrombocytopenic purpura in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted TAVALISSE Sales Data from 2023 to 2032.

• TAVALISSE Clinical Trials Assessment

The report provides the clinical trials information of TAVALISSE for thrombocytopenia and immune thrombocytopenic purpura covering trial interventions, trial conditions, trial status, start and completion dates.

TAVALISSE Market Forecast Report Highlights 

• In the coming years, the TAVALISSE market scenario for thrombocytopenia and immune thrombocytopenic purpura is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug TAVALISSE manufacturers to penetrate more into the market.  
• The TAVALISSE Companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence TAVALISSE dominance.
• Other emerging TAVALISSE Products for thrombocytopenia and immune thrombocytopenic purpura are expected to give tough market competition to TAVALISSE and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of TAVALISSE in thrombocytopenia and immune thrombocytopenic purpura.
• Our in-depth analysis of the forecasted TAVALISSE Sales Data from 2023 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the TAVALISSE in thrombocytopenia and immune thrombocytopenic purpura.

Key Questions

• What is the TAVALISSE Product type, route of administration and TAVALISSE Mechanism of Action?
• What is the clinical trial status of the study related to TAVALISSE in thrombocytopenia and immune thrombocytopenic purpura and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the TAVALISSE development?
• What are the key designations that have been granted to TAVALISSE for thrombocytopenia and immune thrombocytopenic purpura?
• What is the forecasted market scenario of TAVALISSE for thrombocytopenia and immune thrombocytopenic purpura?
• What are the forecasted TAVALISSE Sales in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan? 
• What are the other emerging TAVALISSE Products available and how are these giving competition to TAVALISSE for thrombocytopenia and immune thrombocytopenic purpura?
• Which are the late-stage emerging therapies under development for the treatment of thrombocytopenia and immune thrombocytopenic purpura?

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