Jan 20, 2017
Fragile X syndrome (FXS) is an inherited genetic condition that causes mental retardation, intellectual disability, and autism. Etiology of the disease includes the defect in the FMR1 gene located on the X-chromosome, which prevents the gene from properly synthesising a protein called the fragile X mental retardatio...
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Jan 19, 2017
With Flublok at a standstill in Japan, Astellas ditches collaborator UMN Pharma After Japanese regulators turned away the partners’ submission for a new cell-culture flu vaccine, Astellas has pulled the plug on a collaboration with UMN Pharma. UMN said it’s “regrettable” the companies can no longer work together to ...
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Jan 18, 2017
A study, Analysis of Surveillance, Epidemiology, and End Results (SEER), has shed light on the increased prevalence of incidence of distant metastasis at diagnosis in men aged ≥75 years with prostate cancer. This increase is most probably the result of a recommendation provided by the US Preventative Services Task F...
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Jan 17, 2017
US FDA accepts Mylan’s BLA for proposed trastuzumab product Biocon and Mylan have announced acceptance of the latter’s biologics licence application (BLA) by the US Food and Drug Administration (FDA) for MYL-1401O, a proposed biosimilar trastuzumab. Mylan’s MYL-1401O is indicated to treat certain HER2-positive breas...
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Jan 16, 2017
Microbiome refers to the collection of microbes and their interaction with the human body. Human body possess a number of different species, particularly bacteria and fungi, which help in digesting food, preventing infections, perform numerous life-supporting tasks. Microbiome and metagenome have important fun...
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Jan 13, 2017
The high cost of pharmaceuticals, especially Biologics, has been proven as an issue in the battle to control healthcare costs. The Biologics Price Competition and the Innovation Act has put forward the generic competition of Biologics or what is popularly called the Biosimilars. Biosimilars have been available in th...
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Jan 12, 2017
Aurobindo takes top generic spot in Portugal with €135M deal for Generis Farmacêutica India’s Aurobindo Pharma, which has been building its presence around the world, has struck a new deal to buy a generics manufacturer and plant in Portugal which it says will make it the largest generics manufacturer in that countr...
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Jan 11, 2017
Apoptosis and necrosis are considered to be distinct modes of cell death; however, apoptosis can progress to secondary necrosis if apoptotic cells are not efficiently removed by phagocytic cells. Secondary necrosis was thought to be unregulated and to occur through passive cell swelling. However, research shows that...
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Jan 09, 2017
Mammalian Target of Rapamycin (mTOR) is always in limelight for its wider application. It is a protein of a 289-kDa long chain contains serine and threonine kinase, and was first identified when rapamycin (Sirolimus) was discovered. mTOR helps in the synthesis of important cellular proteins which has a major impact ...
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