Spinal Muscular
Atrophy (SMA) is a genetic disorder that affects the part of the nervous
system which controls the voluntary movement of limbs and muscles. SMA results
in the loss of motor neurons in the Spinal Cord. SMA is one of the most common
causes of infant mortality and mobility impairment. Spinal Muscular Atrophy is caused by the mutations in chromosome 5 of
the SMN1 gene. No- SMN1 Mutation and other mutations are also found to be
responsible for the occurrence of Spinal Muscular Atrophy. Defect in the SMN
gene further leads to the deficiency of SMA protein. There are multiple copies
of SMA2 gene as well, but they aren’t as effective as SMN1 gene.
The Spin...
