Wiskott - Aldrich syndrome (also known as WAS) is a rare X-linked recessive genetic disorder that affects both T-lymphocytes and B-lymphocytes. It occurs due to the mutations caused in the WASp gene and is mainly characterized by low platelet count (microthrombocytopenia), immune deficiency, and eczema.
Being an X-linked disorder, it occurs almost exclusively in the male population with an incidence of 4 in 1 million live births in the United States. A similar incidence is observed ex-US. The incidence data from the 7MM including US, UK, Germany, Spain, Italy, France and Japan in 2015 showed that there were only 33 incident cases of WAS. The presentation of the diseas...
