Respiratory Diseases

Cystic fibrosis (CF) manifests as a clinical syndrome characterized by chronic sinopulmonary infection as well as by gastrointestinal, nutritional, and other abnormalities. Lung damage secondary to chronic infection is the main determinant of morbidity and mortality in individuals with cystic fibrosis. CF individuals are highly susceptible to bacterial infections in the respiratory tract and repeated and intensive antibiotic therapy is required to maintain lung function and quality of life and reduce exacerbations in infected patients. According to a study conducted by Jeffrey et al., 2002 it is estimated that 80–95% of patients with CF succumb to respiratory fa...