Cystic fibrosis (CF) manifests as a clinical syndrome
characterized by chronic sinopulmonary infection as well as by
gastrointestinal, nutritional, and other abnormalities.
Lung damage secondary to chronic infection is the main
determinant of morbidity and mortality in individuals with cystic fibrosis. CF
individuals are highly susceptible to bacterial infections in the respiratory
tract and repeated and intensive antibiotic therapy is required to maintain
lung function and quality of life and reduce exacerbations in infected
patients.
According to a study conducted by Jeffrey et al., 2002 it is
estimated that 80–95% of patients with CF succumb to respiratory fa...
