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Surgical Site Infections (SSI) - Market Insight, Epidemiology and Market Forecast - 2028

Published Date : 2019

Pages : 147

Region : United States, Japan, EU4 & UK

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surgical site infections ssi market size

DelveInsight's "Surgical Site Infections (SSI) - Market Insights, Epidemiology and Market Forecast-2028" report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the market trends of SSI in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.

The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Surgical Site Infections from 2017 to 2028 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.

Geography Covered

• The United States

• EU5 (Germany, France, Italy, Spain and the United Kingdom)

• Japan

Study Period: 2017-2028

Surgical Site Infections (SSI) - Disease Understanding and Treatment Algorithm

The DelveInsight Surgical Site Infection epidemiology report gives the thorough understanding of the SSI by including details such as disease definition, classification, symptoms, risk factors, pathogenesis, and diagnostic trends. It also provides treatment algorithms and treatment guidelines for Surgical Site Infection in the US, Europe, and Japan.

Surgical Site Infection (SSI) Epidemiology

The Surgical Site Infection (SSI) epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the current and forecasted trends by exploring numerous studies, public databases, and views of key opinion leaders. This part of the DelveInsight report provides the total number of surgical procedures performed each year and incidence of surgical site infections, along with their trends and assumptions undertaken.

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology (total surgical procedures, total incidence cases of SSI, and type-specific incidence cases) scenario of Surgical Site Infection (SSI) in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2017-2028.

According to DelveInsight, total incident population of Surgical Site Infection (SSI) in 7 major markets was found to be 1,101,182 in 2017.

Surgical Site Infection (SSI) Drug Chapters

This segment of the Surgical Site Infection report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval, advantages and disadvantages of each included drug and the latest news and press releases.

At present, therapeutic classes of drugs contributing towards the market size of SSI includes, the topical or oral or injectable prophylactic antibiotics used for preoperative, intraoperative and postoperative procedures. The prophylactic therapy drug market is dominated by generic antibiotics, and most common drugs include antibiotics such as: Cefazolin, Vancomycin, Cefuroxime, Clindamycin, Cefotetan, Metronidazole and Gentamicin. On other hand Surgical Site Infection (SSI) Treatment drug market is based on antibiotics such as Vancomycin and Linezolid (Cardiothoracic / related leg SSI) and Tigecycline IV (Abdominal SSI).

The emerging drugs offer certain improvement in treatment and prevention approached relative to the current medicinal products. These include Prophylactic Therapy D-PLEX100 and XF-73 under-development by PolyPid Ltd. And Destiny Pharma respectively, while Delafloxacin (Menarini Group) being the only upcoming therapy for patient with incisional, superficial or deep, surgical site infection treatment. Detailed chapter for these upcoming therapies have also been covered in the report.

Surgical Site Infection Market Outlook

The Surgical Site Infection market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better approach.

This segment gives a through detail of market trend of each marketed drug class and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to DelveInsight, the treatment market of Surgical Site Infection in 7MM was found to be USD 855 million in 2017.

Surgical Site Infection Drugs Uptake

This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2017-2028. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Surgical Site Infection Report Insights

• Patient Population

• Therapeutic Approaches

• Pipeline Analysis

• Market Size and Trends

• Market Opportunities

• Impact of upcoming Therapies

Surgical Site Infection Report Key Strengths

• 10 Year Forecast

• 7MM Coverage

• Epidemiology Segmentation

• Drugs Uptake

• Highly Analyzed Market

• Key Cross Competition

Surgical Site Infection Report Assessment

• Current Treatment Practices

• Unmet Needs

• Detailed Pipeline Product Profiles

• Market Attractiveness

• Market Drivers and Barriers

Key Benefits

• This DelveInsight report will help to develop Business Strategies by understanding the trends shaping and driving Surgical Site Infection market

• Organize sales and marketing efforts by identifying the best opportunities for Surgical Site Infection market

• To understand the future market competition in the Surgical Site Infection market.

1. Key Insights

2. Prophylaxis Market Overview at a Glance

2.1. Market Share (%) Distribution of Prophylaxis Market in 2017

2.2. Market Share (%) Distribution of Prophylaxis Market in 2028

3. Surgical Site Infection Market Overview at a Glance

3.1. Market Share (%) Distribution of Surgical Site Infection Market in 2017

3.2. Market Share (%) Distribution of Surgical Site Infection Market in 2028

4. Disease Background and Overview

4.1. Types of Surgical Site Infections (SSIs)

4.2. Sign and Symptoms of Surgical Site Infections (SSIs)

4.3. Causes of Surgical Site Infections (SSIs)

4.4. Risk Factors of Surgical Site Infections (SSIs)

4.4.1. Assessing Patient Risks during the Preoperative Phase

4.4.2. Modifiable and Non-Modifiable Host Risk Factors

4.4.3. Extrinsic or External Risk Factors

4.5. Pathogenesis of Surgical Site Infections (SSIs)

4.6. Diagnosis of Surgical Site Infections (SSIs)

4.6.1. Diagnosis Based on Types

4.6.2. Diagnosis Based on Microbes

5. Epidemiology and Patient Population

5.1. Key Findings

5.2. 7MM Total Patient Population of Surgical Site Infections

6. Country Wise-Epidemiology of Surgical Site Infections

6.1. United States

6.1.1. Assumptions and Rationale

6.1.2. Total Surgical Procedures in the United States

6.1.3. Number of Surgical Procedures by types in the United States

6.1.4. Total Incidence Cases of Surgical Site Infections in the United States

6.1.5. Incidence of Surgical Site Infections by types in the United States

6.2. EU5 Countries

6.2.1. Assumptions and Rationale

6.3. Germany

6.3.1. Total Surgical Procedures in Germany

6.3.2. Number of Surgical Procedures by types in Germany

6.3.3. Total Incidence Cases of Surgical Site Infections in Germany

6.3.4. Incidence of Surgical Site Infections by types in Germany

6.4. France

6.4.1. Total Surgical Procedures in France

6.4.2. Number of Surgical Procedures by types in France

6.4.3. Total Incidence Cases of Surgical Site Infections in France

6.4.4. Incidence of Surgical Site Infections by types in France

6.5. Italy

6.5.1. Total Surgical Procedures in Italy

6.5.2. Number of Surgical Procedures by types in Italy

6.5.3. Total Incidence Cases of Surgical Site Infections in Italy

6.5.4. Incidence of Surgical Site Infections by types in Italy

6.6. Spain

6.6.1. Total Surgical Procedures in Spain

6.6.2. Number of Surgical Procedures by types in Spain

6.6.3. Total Incidence Cases of Surgical Site Infections in Spain

6.6.4. Incidence of Surgical Site Infections by types in Spain

6.7. United Kingdom

6.7.1. Total Surgical Procedures in the UK

6.7.2. Number of Surgical Procedures by types in the UK

6.7.3. Total Incidence Cases of Surgical Site Infections in the UK

6.7.4. Incidence of Surgical Site Infections by types in the UK

6.8. Japan

6.8.1. Assumptions and Rationale

6.8.2. Total Surgical Procedures in Japan

6.8.3. Number of Surgical Procedures by types in Japan

6.8.4. Total Incidence Cases of Surgical Site Infections in Japan

6.8.5. Incidence of Surgical Site Infections by types in Japan

7. Treatment

7.1. Treatment Algorithm of Surgical Site Infections (SSIs)

8. Prevention

8.1. Prevention of Surgical Site Infections (SSIs)

8.1.1. Preoperative Measures

8.1.2. Intraoperative Measures

8.1.3. Postoperative Measures

8.1.4. Antibiotic Prophylaxis (AP)

8.2. Prevention Guideline for Surgical Site Infections (SSIs)

8.2.1. Centers for Disease (CDC): Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017

8.2.2. World Health Organization (WHO): Global Guidelines for the Prevention of Surgical Site Infection

8.2.3. National Institute for Health and Care Excellence (NICE): Surgical Site Infections: Prevention and Treatment Guidelines

9. Unmet Needs

10. Emerging drugs

10.1. XF-73: Destiny Pharma

10.1.1. Product Description

10.1.2. Product Development Activities

10.1.3. Clinical development

10.1.4. Clinical Trials Information

10.1.5. Safety and Efficacy

10.1.6. Product Profile

10.2. D-PLEX100: PolyPid

10.2.1. Product Description

10.2.2. Product Development Activities

10.2.3. Clinical development

10.2.4. Clinical Trials Information

10.2.5. Safety and Efficacy

10.2.6. Product Profile

10.3. Delafloxacin: Menarini Group

10.3.1. Product Description

10.3.2. Product Development Activities

10.3.3. Clinical development

10.3.4. Clinical Trials Information

10.3.5. Product Profile

11. Surgical Site Infections: 7 Major Market Analysis

11.1. Key Findings

11.2. Prophylaxis Market Size of Surgical Procedures in 7MM

11.3. Market Size of Surgical Site Infections Treatment in 7MM

12. The United States Market Outlook

12.1. United States Market Size

12.1.1. Surgical Procedures- Prophylaxis Market Size

12.1.2. Prophylaxis Market Size by Therapy

12.1.3. Surgical Site Infections - Treatment Market Size

12.1.4. Surgical Site Infections -Treatment Market Size by Therapy

13. EU-5 Countries: Market Outlook

13.1. Germany

13.1.1. Surgical Procedures- Prophylaxis Market Size

13.1.2. Prophylaxis Market Size by Therapy

13.1.3. Surgical Site Infections - Treatment Market Size

13.1.4. Surgical Site Infections -Treatment Market Size by Therapy

13.2. France

13.2.1. Surgical Procedures- Prophylaxis Market Size

13.2.2. Prophylaxis Market Size by Therapy

13.2.3. Surgical Site Infections - Treatment Market Size

13.2.4. Surgical Site Infections -Treatment Market Size by Therapy

13.3. Italy

13.3.1. Surgical Procedures- Prophylaxis Market Size

13.3.2. Prophylaxis Market Size by Therapy

13.3.3. Surgical Site Infections - Treatment Market Size

13.3.4. Surgical Site Infections -Treatment Market Size by Therapy

13.4. Spain

13.4.1. Surgical Procedures- Prophylaxis Market Size

13.4.2. Prophylaxis Market Size by Therapy

13.4.3. Surgical Site Infections - Treatment Market Size

13.4.4. Surgical Site Infections -Treatment Market Size by Therapy

13.5. The United Kingdom

13.5.1. Total Procedures- Prophylaxis Market Size

13.5.2. Prophylaxis Market Size by Therapy

13.5.3. Surgical Site Infections - Treatment Market Size

13.5.4. Surgical Site Infections -Treatment Market Size by Therapy

14. Japan: Market Outlook

14.1. Japan market Size

14.1.1. Total Market Size Prophylaxis Market Size

14.1.2. Prophylaxis Market Size by Therapy

14.1.3. Surgical Site Infections - Treatment Market Size

14.1.4. Surgical Site Infections -Treatment Market Size by Therapy

15. Market Drivers

16. Market Barriers

17. Appendix

17.1. Report Methodology

18. DelveInsight Capabilities

19. Disclaimer

20. About DelveInsight

List of Tables:

Table 1: Types of Surgical Site Infections (SSIs)

Table 2: Pathogens commonly associated with different surgical procedures

Table 3: Host (Intrinsic or Internal) Characteristics in Surgical Patients

Table 4: Types of Surgical Site Infections (SSIs)

Table 5: Total Population of Surgical Site Infections in the 7MM (2017-2028)

Table 6: Total Surgical Procedures in the United States (2017-2028)

Table 7: Number of surgical procedure by types in the United States (2017-2028)

Table 8: Total Incidence cases of Surgical Site Infections in the United States (2017-2028)

Table 9: Incidence of Surgical Site Infections by types in the United States (2017-2028)

Table 10: Total Surgical Procedures in Germany (2017-2028)

Table 11: Number of surgical procedure by types in Germany (2017-2028)

Table 12: Total Incidence cases of Surgical Site Infections in Germany (2017-2028)

Table 13: Incidence of Surgical Site Infections by types in Germany (2017-2028)

Table 14: Total Surgical Procedures in France (2017-2028)

Table 15: Number of surgical procedure by types in France (2017-2028)

Table 16: Total Incidence cases of Surgical Site Infections in France (2017-2028)

Table 17: Incidence of Surgical Site Infections by types in France (2017-2028)

Table 18: Total Surgical Procedures in Italy (2017-2028)

Table 19: Number of surgical procedure by types in Italy (2017-2028)

Table 20: Total Incidence cases of Surgical Site Infections in Italy (2017-2028)

Table 21: Incidence of Surgical Site Infections by types in Italy (2017-2028)

Table 22: Total Surgical Procedures in Spain (2017-2028)

Table 23: Number of surgical procedure by types in Spain (2017-2028)

Table 24: Total Incidence cases of Surgical Site Infections in Spain (2017-2028)

Table 25: Incidence of Surgical Site Infections by types in Spain (2017-2028)

Table 26: Total Surgical Procedures in The UK (2017-2028)

Table 27: Number of surgical procedure by types in The UK (2017-2028)

Table 28: Total Incidence cases of Surgical Site Infections in The UK (2017-2028)

Table 29: Incidence of Surgical Site Infections by types in The UK (2017-2028)

Table 30: Total Surgical Procedures in Japan (2017-2028)

Table 31: Number of surgical procedure by types in Japan (2017-2028)

Table 32: Total Incidence cases of Surgical Site Infections in Japan (2017-2028)

Table 33: Incidence of Surgical Site Infections by types in Japan (2017-2028)

Table 34: Surgical Site Infection (SSI) Treatment Algorithm

Figure 35: Principles of Antibiotic Prophylaxis:

Table 36: Most Commonly Prescribed Agents for Patients Who Received Any Antimicrobial or Combination of Antimicrobials Consistent With Surgical Antimicrobial Prophylaxis Guidelines*

Table 37: Summary of core topics, research questions and recommendations for the prevention of surgical site infection.

Table 38: Options for Antiseptic Skin Preparation

Table 39: XF-73, Clinical Trial Description, 2019

Table 40: D-PLEX100 , Clinical Trial Description, 2019

Table 41: Delafloxacin , Clinical Trial Description, 2019

Table 42: Prophylaxis Market Size of Surgical Procedures in 7MM in USD Million (2017-2028)

Table 43: Market Size of Surgical Site Infections Treatment in 7MMin USD Million (2017-2028)

Table 44: Surgical Procedures- Prophylaxis Market Size in the US, USD Million (2017-2028)

Table 45: Prophylaxis Market Size by Therapy in the US, in USD Million (2017-2028)

Table 46: Surgical Site Infections - Treatment Market Size in the US, USD Million (2017-2028)

Table 47: Surgical Site Infections -Treatment Market Size by Therapy in the US, in USD Million (2017-2028)

Table 48: Surgical Procedures- Prophylaxis Market Size in Germany, USD Million (2017-2028)

Table 49: Prophylaxis Market Size by Therapy in Germany, in USD Million (2017-2028)

Table 50: Surgical Site Infections - Treatment Market Size in Germany, USD Million (2017-2028)

Table 51: Surgical Site Infections -Treatment Market Size by Therapy in Germany, in USD Million (2017-2028)

Table 52: Surgical Procedures- Prophylaxis Market Size in France, USD Million (2017-2028)

Table 53: Prophylaxis Market Size by Therapy in France, in USD Million (2017-2028)

Table 54: Surgical Site Infections - Treatment Market Size in France, USD Million (2017-2028)

Table 55: Surgical Site Infections -Treatment Market Size by Therapy in France, in USD Million (2017-2028)

Table 56: Surgical Procedures- Prophylaxis Market Size in Italy, USD Million (2017-2028)

Table 57: Prophylaxis Market Size by Therapy in Italy, in USD Million (2017-2028)

Table 58: Surgical Site Infections - Treatment Market Size in Italy, USD Million (2017-2028)

Table 59: Surgical Site Infections -Treatment Market Size by Therapy in Italy, in USD Million (2017-2028)

Table 60: Surgical Procedures- Prophylaxis Market Size in Spain, USD Million (2017-2028)

Table 61: Prophylaxis Market Size by Therapy in Spain, in USD Million (2017-2028)

Table 62: Surgical Site Infections - Treatment Market Size in Spain, USD Million (2017-2028)

Table 63: Surgical Site Infections -Treatment Market Size by Therapy in Spain, in USD Million (2017-2028)

Table 64: Surgical Procedures- Prophylaxis Market Size in The UK, USD Million (2017-2028)

Table 65: Prophylaxis Market Size by Therapy in The UK, in USD Million (2017-2028)

Table 66: Surgical Site Infections - Treatment Market Size in The UK, USD Million (2017-2028)

Table 67: Surgical Site Infections -Treatment Market Size by Therapy in The UK, in USD Million (2017-2028)

Table 68: Surgical Procedures- Prophylaxis Market Size in Japan, USD Million (2017-2028)

Table 69: Prophylaxis Market Size by Therapy in Japan, in USD Million (2017-2028)

Table 70: Surgical Site Infections - Treatment Market Size in Japan, USD Million (2017-2028)

Table 71: Surgical Site Infections -Treatment Market Size by Therapy in Japan, in USD Million (2017-2028)

List of Figures:

Figure 1: Total Diagnosed Patient Population of Surgical Site Infections in the 7MM (2017-2028)

Figure 2: Total Surgical Procedures in the United States (2017-2028)

Figure 3: Number of surgical procedure by types in the United States (2017-2028)

Figure 4: Total Incidence cases of Surgical Site Infections in the United States (2017-2028)

Figure 5: Incidence of Surgical Site Infections by types in the United States (2017-2028)

Figure 6: Total Surgical Procedures in Germany (2017-2028)

Figure 7: Number of surgical procedure by types in Germany (2017-2028)

Figure 8: Total Incidence cases of Surgical Site Infections in Germany (2017-2028)

Figure 9: Incidence of Surgical Site Infections by types in Germany (2017-2028)

Figure 10: Total Surgical Procedures in France (2017-2028)

Figure 11: Number of surgical procedure by types in France (2017-2028)

Figure 12: Total Incidence cases of Surgical Site Infections in France (2017-2028)

Figure 13: Incidence of Surgical Site Infections by types in France (2017-2028)

Figure 14: Total Surgical Procedures in Italy (2017-2028)

Figure 15: Number of surgical procedure by types in Italy (2017-2028)

Figure 16: Total Incidence cases of Surgical Site Infections in Italy (2017-2028)

Figure 17: Incidence of Surgical Site Infections by types in Italy (2017-2028)

Figure 18: Total Surgical Procedures in Spain (2017-2028)

Figure 19: Number of surgical procedure by types in Spain (2017-2028)

Figure 20: Total Incidence cases of Surgical Site Infections in Spain (2017-2028)

Figure 21: Incidence of Surgical Site Infections by types in Spain (2017-2028)

Figure 22: Total Surgical Procedures in The UK (2017-2028)

Figure 23: Number of surgical procedure by types in The UK (2017-2028)

Figure 24: Total Incidence cases of Surgical Site Infections in The UK (2017-2028)

Figure 25: Incidence of Surgical Site Infections by types in The UK (2017-2028)

Figure 26: Total Surgical Procedures in Japan (2017-2028)

Figure 27: Number of surgical procedure by types in Japan (2017-2028)

Figure 28: Total Incidence cases of Surgical Site Infections in Japan (2017-2028)

Figure 29: Incidence of Surgical Site Infections by types in Japan (2017-2028)

Figure 30: Unmet Needs

Figure 31: Prophylaxis Market Size of Surgical Procedures in 7MM in USD Million (2017-2028)

Figure 32: 10.3

Figure 33: Surgical Procedures- Prophylaxis Market Size in the United States, USD Millions (2017-2028)

Figure 34: Prophylaxis Market Size by Therapy in the US, in USD Million (2017-2028)

Figure 35: Surgical Site Infections - Treatment Market Size in the United States, USD Millions (2017-2028)

Figure 36: Surgical Site Infections -Treatment Market Size by Therapy in the US, in USD Million (2017-2028)

Figure 37: Surgical Procedures- Prophylaxis Market Size in Germany, USD Millions (2017-2028)

Figure 38: Prophylaxis Market Size by Therapy in Germany, in USD Million (2017-2028)

Figure 39: Surgical Site Infections - Treatment Market Size in Germany, USD Millions (2017-2028)

Figure 40: Surgical Site Infections -Treatment Market Size by Therapy in Germany, in USD Million (2017-2028)

Figure 41: Surgical Procedures- Prophylaxis Market Size in France, USD Millions (2017-2028)

Figure 42: Prophylaxis Market Size by Therapy in France, in USD Million (2017-2028)

Figure 43: Surgical Site Infections - Treatment Market Size in France, USD Millions (2017-2028)

Figure 44: Surgical Site Infections -Treatment Market Size by Therapy in France, in USD Million (2017-2028)

Figure 45: Surgical Procedures- Prophylaxis Market Size in Italy, USD Millions (2017-2028)

Figure 46: Prophylaxis Market Size by Therapy in Italy, in USD Million (2017-2028)

Figure 47: Surgical Site Infections - Treatment Market Size in Italy, USD Millions (2017-2028)

Figure 48: Surgical Site Infections -Treatment Market Size by Therapy in Italy, in USD Million (2017-2028)

Figure 49: Surgical Procedures- Prophylaxis Market Size in Spain, USD Millions (2017-2028)

Figure 50: Prophylaxis Market Size by Therapy in Spain, in USD Million (2017-2028)

Figure 51: Surgical Site Infections - Treatment Market Size in Spain, USD Millions (2017-2028)

Figure 52: Surgical Site Infections -Treatment Market Size by Therapy in Spain, in USD Million (2017-2028)

Figure 53: Surgical Procedures- Prophylaxis Market Size in The UK, USD Millions (2017-2028)

Figure 54: Prophylaxis Market Size by Therapy in The UK, in USD Million (2017-2028)

Figure 55: Surgical Site Infections - Treatment Market Size in The UK, USD Millions (2017-2028)

Figure 56: Surgical Site Infections -Treatment Market Size by Therapy in The UK, in USD Million (2017-2028)

Figure 57: Surgical Procedures- Prophylaxis Market Size in Japan, USD Millions (2017-2028)

Figure 58: Prophylaxis Market Size by Therapy in Japan, in USD Million (2017-2028)

Figure 59: Surgical Site Infections - Treatment Market Size in Japan, USD Millions (2017-2028)

Figure 60: Surgical Site Infections -Treatment Market Size by Therapy in Japan, in USD Million (2017-2028)

Figure 61: Market Drivers

Figure 62: Market Barriers

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