All Blogs

Sep 05, 2016

Immune checkpoint activators are small molecules responsible for maintenance, modulation and regulation of immune responses. Its significance in Immuno therapeutics is backed by its functionality to activate the immune checkpoint proteins that are down regulated by tumors, leading to the activation of the immune sys...

Sep 02, 2016

Game changing agent, Opdivo, on a threshold to change standard of care in squamous cell carcinoma of the head and neck (SCCHN) According to Dr. Robert Ferris, who is vice chair for Clinical Operations, associate director for Translational Research, and co-leader of the Cancer Immunology Program at the University of ...

Sep 01, 2016

There has been a shocking revelation in a report published in Science Translational Medicine by Bengt Westermark, a tumour biologist at Uppsala, who reports that a cell line widely used to study brain cancer does not match the cells used to create the line nearly 50 years ago, or the tumour supposed to be its source...

Aug 31, 2016

Boehringer Ingelheim Pharmaceuticals and the Duke Clinical Research Institute have expanded their collaboration to create the largest patient registry for Idiopathic Pulmonary Fibrosis (IPF) The IPF-PRO Registry will be widened to cover 1500 patients spread over 45 clinical sites which will stimulate understand...

Aug 30, 2016

Mylan’s EpiPen is used as a lifesaver to threatening allergic reactions. It mitigates or reverses allergic reactions including abrupt blocking of airways and swollen legs, chest or neck.  In late 2007, Mylan acquired the rights to sell EpiPen, an invention of the 1970s. Even its inventor Sheldon Kaplan did not know ...

Aug 26, 2016

The South San Francisco biotech startup, Denali Therapeutics, that had raised $217 million last year to fight Alzheimer’s, Parkinson’s and ALS, and an additional  $130 million from investors in a private placement led by Baillie Gifford, a UK-based mutual fund, has finally spoken about its plans to use the fund. The...

Aug 25, 2016

NATCO Pharma surges 7% post successful Establishment Inspection Report for Chennai Plant NATCO pharma has reached a new high of Rs. 703 on the National Stock Exchange (NSE) as the drug maker revealed the successful Establishment Inspection Report (EIR) for Chennai Plant. The U.S. Food and Drug Administration (FDA) h...

Aug 24, 2016

Partnership between Bristol Meyers Squibb and AbbVie aims to evaluate the Combination of Rova-T plus Opdivo and Opdivo plus Yervoy Regimen Bristol Meyers Squibb and AbbVie have undergone an oncology clinical collaboration to develop a treatment option for patients with relapsed extensive-stage small cell lung cancer...

Aug 23, 2016

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), a gene-editing technology, has set a record by reaching clinics from the research laboratory in a very short time, as NIH’s Recombinant DNA Advisory Committee has approved the first clinical trial of the technology in the U.S. for coming June. The t...

Aug 22, 2016

Voltage-gated sodium channels are membrane proteins, a polypeptide chain of more than 1800 amino acids that conduct sodium ions at high rates. They are embedded in the plasma membrane and are actively present in the nerve and muscle cells used in the rapid electrical signaling. Nav channels are therapeutic targets f...