Endocrinology and Metabolic Disorders

Cushing’s syndrome, also known as hypercortisolism, is an endocrine disorder that occurs due to abnormally high levels of the hormone cortisol production in the body. Cushing’s syndrome is broadly classified as endogenous and exogenous Cushing’s syndrome. Exogenous Cushing’s syndrome occurs due to excessive use of medications like glucocorticosteroids while endogenous cushing syndrome may be due to ACTH dependent causes or ACTH independent causes. The incidence is around 1.2-1.7 per million per year for Cushing's disease (CD), 0.6 per million per year for adrenal adenomas and 0.2 per million per year for adrenal carcinomas. All the other types of CS are very rare. End...