Cushing’s disease is a rare but serious endocrine disorder caused by a pituitary adenoma that leads to excessive secretion of ACTH. This condition results in abnormally high cortisol levels in the body, causing a cascade of serious health complications. Cushing’s syndrome, the clinical manifestation of this disorder, accounts for 80-85% of all hypercortisolism cases, with Cushing’s disease responsible for 75-80% of these cases. The clinical significance of this condition cannot be overstated, as the estimated 5-year survival rate for untreated Cushing’s disease is only 50%, highlighting the critical need for effective treatments.
Based on DelveInsight’s 2024 assess...
