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“We designed CAR T cells to overcome a number of problems in getting T cells to attack Cancer”-says Eshhar, after the development of first CAR-T cells (1989). CAR-T Technologies and History of Innovations Ever so often in the history of immunotherapy, there comes a breakthrough that takes cancer research across a frontier into a new era. With the development of first CAR-T cells started in the late 1990s and the emergence of new CARs generations with promising study results targeting cancer indications has given a big blow to the immunotherapy market. Even with these encouraging preliminary findings, the adverse events associated with CAR-T cell therapy a...
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