Pharmaceutical

Natural killer cells are the innate immune cells that are naturally involved in tumor immunosurveillance. These cells have direct cytotoxic activity and also secrete proinflammatory cytokines upon activation. Natural killer cells’ cytolytic activity is dependent on a balance between inhibitory signals and activating signals provided by the host cells. These demonstrate particular promise for cellular therapy, as they can identify and eliminate tumors that have altered major histocompatibility class I expression. The therapeutic development based on Natural Killer Cell Therapies deals with around 40+ active pipeline drugs including major products of NantKwest, Sorrento...