Pharmaceutical

Fatty acid amide hydrolase (FAAH) belongs to the serine hydrolase family of enzymes. The identification of this enzyme was led by the discovery and characterization of fatty acid amides, including anandamide and oleamide, as a fundamental class of endogenous signaling molecules. FAAH serves as the major metabolic regulator of many of the endogenous fatty acid amides, exhibiting a distribution consistent with its role in regulating their effects at their released sites of action. A number of research studies have demonstrated that genetic and pharmacological inactivation of FAAH produces analgesic, anti-inflammatory, anxiolytic, neurogenic, neuropsychiatric, and anti-de...