The GvHD drugs treatment landscape is undergoing a dynamic transformation, driven by a wave of innovation aimed at improving patient outcomes and quality of life. Once dominated by steroids and broad immunosuppressants, the field is now witnessing a surge in targeted therapies, cellular approaches, and novel biologics designed to precisely modulate the immune response.
The GvHD treatment landscape has seen a wave of FDA approvals over the years. IMBRUVICA (AbbVie/Janssen) made history in 2017 as the first FDA-approved therapy for chronic GvHD. This was followed by JAKAFI (Incyte Corporation/Novartis) in 2019 for steroid-refractory acute GvHD and ORENCIA (Bristol My...