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Janus Kinase (JAK) inhibitors are the ones that inhibit the functional activity of enzymes that belong to Janus Kinase family such as JAK1, JAK2, JAK3 and TYK2 by interfering in the JAK-STAT signaling pathway. JAK Inhibitors are used for the treatment purpose in cancer and inflammatory diseases like rheumatoid arthritis. Studies conducted by team of Professor Angela Christiano at Columbia University suggested that JAK Inhibitors are also beneficial for treatment of autoimmune dermatological disease like alopecia Areata, a condition in which body’s natural immune system starts attacking hair follicles that lead to loss of hair on scalp or on other parts of bod...
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