Japan's largest drugmaker Takeda has successfully closed a deal worth USD 62 billion to buy another pharma giant Shire grabbing a place in the top 10 pharmaceutical company list. This is the biggest pharma acquisition of this year so far. Takeda was trying to close a deal for quiet a long time and the news came on tuesday when the official announced that both the companies have made an agreement. The final valuation of Dublin based shire is set at USD 62.1 billion, excluding debt according to the officials. Including shire's debt the buyout is worth USD 80 billion making it biggest deal ever signed by a japanese pharmaceutical company. Takeda has a market value of around USD 33 billion and the deal has left the investors in fear of how to fund the acquisition. After this deal they will enter into the western markets opening new horizons for its growth.