Top 12 Most Expensive Drugs in the US Healthcare Market

Cell and Gene Therapy

A CRISPR WAY TO USE STEM CELLS

Stem Cells therapies and CRISPR gene-editing are not new. Having able to grow the desired cells and manipulate the genome system have proved to be the most important breakthrough so far. We all are...

Feb 25, 2019

CRISPR
CRISPR proves to be a blessing for LASSA fever

The ability of CRISPR to change an organism’s DNA has lead researchers, particularly from Nigeria to use the tool to perform diagnostic tests. Since CRISPR therapeutics is all about targeting the genome-specific sequence, the test is believed to pinpoint the exact viral strain circulating. The recent epidemi...

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Kidney Cancer
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CRISPR treatment delivers benefits in mice The researchers from Duke University along with drugmaker Sarepta Therapeutics published a report stating that a single change in the genetic system of Duchenne muscular dystrophy (DMD) affected mice, using CRISPR gene editing tool resulted in increasing their life spa...

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Diabetes
Human cells reprogrammed to create insulin in diabetic mice

Diabetes – a chronic condition in which sugar is not processed in the body. Diabetic people either do not produce enough insulin or cells halt responding to insulin. Due to this, sugar keeps on accumulating in the blood that leads to increased sugar. Gradually, high blood sugar can lead to nerve damage and heart di...

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Peloton Therapeutics
Neurogene raises $68.5M; AbbVie and Teneobio sign deal; 5AM Ventures nets

Neurogene raises USD 68.5 Million for rare neurological diseases Neurogene netted USD 68.5 million to advance multiple gene therapy programs in its series A round. The idea is to take its major programs into IND-enabling studies for Aspartylglucosaminuria (AGU) and a rare form of Charcot-Marie Tooth disease with...

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Genentech remunerates Xencor; XPrize upraises fund; GSK gambles

Genentech remunerates Xencor USD 120 Million for global rights Genentech has remunerated USD 120 million upfront to have global rights to IL-15 cytokine therapeutics in preclinical development at Xencor. Xencor is pursuing IL-15, an immune signaling protein, contemplating that it can stimulate natural...

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Kidney Cancer
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FDA discards depression drug ALKS 5461 of Alkermes The FDA has rejected approval for ALKS 5461 of Alkermes in major depressive disorder. ALKS 5461 is a fixed-dose combination of buprenorphine and samidorphan. Alkermes designed the combination to act on the mu- and kappa-opioid receptors that eventually showed im...

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lung cancer
Molecular Profiling Could Help in Early Lung Cancer Detection: Study

The world's first genetic sequencing of precancerous lung lesions could pave the way for very early detection and new treatments report a new study led by UCL researchers. Before lung cancer develops, precancerous lesions are found in the airway, but only half of these will actually become lung cancer, while others...

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immune
Highly mutated cancers respond better to immune therapy

A survey was done in which thousands of advanced cancers indicated a way to detect those that respond to revolutionary therapies that unleash an immune response against tumours. However, the results show difficulty level to translate an approach into a reliable clinical test. The findings are the latest evidence to...

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patent ductus arteriosus
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Abbott’s pea-sized implant for congenital heart defects gets FDA approval FDA approved Abbott for its Amplatzer Piccolo Occluder, the implant designed for premature babies. The device is used to treat patent ductus arteriosus (PDA), a life-threatening opening in the hearts of premature newborns and is a minimal...

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The gene therapy in rare diseases market has drastically changed recently due to scientific advancem.....

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Soft Tissue Sarcoma (STS) tumors constitute 1% of all the malignancies. These are rare neoplasms tha.....

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Alopecia Areata (AA) is an autoimmune disorder that leads to hair loss on the scalp, face, and on ot.....

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Diabetic retinopathy is an eye condition that leads to vision loss and blindness in people who have .....

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Value-Based Healthcare is that healthcare model or a process where the providers, including hospital.....

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Dry Age-related Macular Degeneration (Dry AMD), also called atrophic AMD, is the most common form of.....

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