AL Amyloidosis is a rare disease, with around 8,500 new cases diagnosed each year in the 7MM. This disease mostly affects elderly persons median age of 64, with slight male predominance (54%). As per our estimates, the highest AL Amyloidosis incidence was observed in the US in 2021. Moreover, there are more than 30 different types of amyloid proteins. Each amyloid protein is structured in a structure known as a fibril, which is made up of low molecular weight proteins produced from precursor proteins. Amyloid fibrils can float in blood plasma and deposit in tissues throughout the body. Amyloid light chain (AL) amyloidosis, commonly known as primary amyloidosis, is the...
