Oncolytic viruses are cancer treatments that employ a natural or reprogrammed virus capable of targeting and killing malignant cells. They are a new class of cancer agents that induce tumor regression by causing immunogenic cell death, inducing preferential replication in tumor cells, and stimulating host antitumor immunity. Oncolytic viruses are experimental cancer treatments that try to employ viruses’ intrinsic features to help fight cancer. These non-human viruses proliferate primarily in cancer cells while disregarding healthy ones.
Oncolytic viruses can create virions fast and genetically design new genes that boost antitumor immunity, make tumor cells more s...