The 2025 San Antonio Breast Cancer Symposium (SABCS), the world’s leading forum for breast cancer research, highlights cutting-edge progress across the full spectrum of breast cancer, from prevention and molecular biology to new therapies and survivorship. This year’s focus includes several emerging strategies to reduce toxicity and improve outcomes in HER2-positive, HER2-negative, and triple-negative breast cancer (TNBC).
TNBC, accounting for about 10–15% of invasive breast cancers, remains a difficult subtype due to the absence of hormone receptors and HER2 expression, limiting targeted options. SABCS 2025 spotlights advances aimed at addressing these gaps ...