World Population Day 2018

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Enhancing Patient Care: Transitioning from Ecul...

Eculizumab (SOLIRIS) and ravulizumab (ULTOMIRIS) are two approved therapies for the treatment for adult patients with generalized Myasthenia Gravis (gMG) who are anti-acetylcholine receptor antibod...

Apr 19, 2024

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Revolutionizing gMG Treatment: Efgartigimod’s Triumph in Curtailing Oral Corticosteroid Dependence

Efgartigimod (VYVGART/VYVGART Hytrulo) is a prescription medicine for the treatment of gMG in adults who are positive for antibodies directed toward a protein called acetylcholine receptor (anti-AChR antibody positive). It is designed as a first-in-class investigational antibody fragment to target the neonatal Fc ...

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Advancing Parkinson’s Disease Treatment: P2B001 Offers Promising Safety Profile in Early PD Patients

P2B001, a novel once-daily combination therapy, uniquely merges extended-release pramipexole and rasagiline in low doses, targeting Parkinson's Disease (PD) with enhanced efficacy and minimized side effects. The analysis presented by Pharma Two B highlighted P2B001's impressive safety and tolerability profile c...

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Unveiling the Promising Long-Term Potential of Subcutaneous Efgartigimod PH20 in Managing gMG

Efgartigimod PH20 is a combination subcutaneous (SC) infusion that contains efgartigimod alfa and hyaluronidase which may be used to improve muscle weakness in adults with generalized myasthenia gravis (gMG) who are anti-AChR antibody positive. The interim results presented by Argenx highlighted notable efficac...

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Evenamide (NW-3509): Advancing Solutions for Treatment-Resistant Schizophrenia

Evenamide (NW-3509)– derived from Newron's ion channel program, tackles schizophrenia with its unique mechanism, balancing glutamate levels and blocking aberrant sodium channel activity to restore neuronal function without compromising normal excitability. Evenamide, based on a new concept in treating inadequat...

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Ulotaront (SEP-363856): A New Era in Schizophrenia Treatment

Ulotaront (SEP-363856), a novel investigational drug, by Sumitomo Pharma/Otsuka Pharmaceuticals, has shown promise as a potential alternative treatment method for schizophrenia, as it lessens the negative metabolic side effects TAAR1 has emerged as a promising target in the treatment of schizophrenia and other ...

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A New Dawn: Emraclidine (CVL-231) and the Quest for Effective Schizophrenia Therapeutics

Unlike traditional antipsychotic medications that block dopamine receptors, CVL-231 selectively modulates the M4 receptor in the brain and provides antipsychotic effects without the need for titration. CVL-231, a once-daily medication, with enhanced potential for treatment adherence, seeks to bypass gastrointes...

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KarXT: Illuminating Pathways in Schizophrenia Treatment

KarXT, likely to receive the nod from the US FDA by late 2024, will significantly impact the market with the potential to reduce the positive, negative, and cognitive symptoms of schizophrenia. The long-term data is encouraging, signaling that KarXT is not associated with “burdensome side effects” the major imp...

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Beyond Symptom Management: RL-007’s Promise for Cognitive Enhancement in Schizophrenia

In the landscape of schizophrenia treatment, there are significant gaps that affect patients' lives profoundly. From the foggy terrain of early detection, where symptoms blur the lines between schizophrenia and other mental health conditions, to the daunting landscape of treatment resistance and relapse, where stan...

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Breaking Boundaries: The Promise of LYN-005 in Schizophrenia Treatment

LYN-005’s once-weekly dosing regimen reduces the pill burden for individuals with schizophrenia and schizoaffective disorders compared to traditional daily medications such as Risperdal. A unique capsule design consisting of six polymeric arms connected to a flexible core, encapsulated in a folded star-shaped f...

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Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection. Se.....

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Metachromatic Leukodystrophy (MLD) is a rare hereditary disease characterized by the accumulation of.....

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Systemic Lupus Erythematosus (SLE) is an autoimmune disease where the immune system of the body mist.....

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An autosomal metabolic disorder – Pompe disease results in deterioration of organs and tissues as .....

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The gene therapy in rare diseases market has drastically changed recently due to scientific advancem.....

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Uremic Pruritusis also known as chronic kidney disease-associated pruritus (CKD-aP), is a chronic it.....

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