Osteosarcomas are rare, yet are the leading cause of deaths due to cancer in the pediatric population. It is a high-grade malignancy of mesenchymal origins. They are the most frequent forms of primary bone tumors and account for approximately 20% of all the bone tumors. With the incident population of less than 2500 in the 7MM (the US, EU5 (the UK, Germany, France, Italy, and Spain), and Japan)in 2017, the rarity of Osteosarcomas makes its management quite bone-breaking.
Surgery has played an integral role in managing Osteosarcoma. Looking back, 40 years or so, the other name for osteosarcoma meant amputation. That was the time when the only option for solvin...