Agios Pharmaceuticals

Feb 22, 2019

Cholangiocarcinoma (BILE Duct cancer) is a type of uncommon CANCER. It arises in Bile ducts. The Bile duct is a long tubule like structure which connects the liver (hepatic duct) to the gall bladder (cystic duct). It carries bile, which helps in digestion of food, from gall-bladder (produced in the liver) to inte...

Sep 22, 2017

The enzyme, isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate and CO2. It is found in the cytosol, mitochondrial matrix, and peroxisomes. IDH is responsible for cellular respiration in the TCA cycle. Isocitrate dehydrogenase exists in three isoforms i...