Orthostatic Hypotension - Market Insight, Epidemiology And Market Forecast - 2034

Published Date : 2026
Pages : 200
Region : United States, Japan, EU4 & UK

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Orthostatic Hypotension Market Summary

  • As per DelveInsight, the Orthostatic Hypotension Market size is expected to expand at a healthy growth rate during the forecast period (2024-2034), owing to the launch of new therapies in the market and the rise in the number of cases. 
  • The Orthostatic Hypotension companies developing therapies include - TSH Biopharm Corporation Limited, Lundbeck LLC, Chelsea Therapeutics, Theravance Biopharma, Juvantia Pharma Ltd, Theravance Biopharma, Shire, and others.

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Key Factors Driving the Orthostatic Hypotension Market

  • Rising Geriatric Population: The growing elderly population is more susceptible to autonomic dysfunction and blood pressure regulation issues, increasing Orthostatic Hypotension prevalence and treatment demand.
  • Increasing Burden of Chronic and Neurological Disorders: Higher incidence of Parkinson’s disease, diabetes, cardiovascular diseases, and neuropathies conditions commonly associated with Orthostatic Hypotension continues to expand the patient pool.
  • Greater Awareness and Improved Diagnosis: Improved clinician awareness, better diagnostic protocols, and wider use of blood pressure monitoring are leading to higher diagnosis rates and earlier treatment initiation.
  • Advancements in Pharmacological Therapies: Availability of approved drugs (e.g., midodrine, droxidopa) and ongoing pipeline development targeting symptom control and quality-of-life improvement support market growth.
  • Focus on Quality of Life and Fall Prevention: Increased emphasis on reducing dizziness, syncope, and fall-related injuries especially in elderly and neurologic patients drives sustained demand for effective Orthostatic Hypotension therapies.

Orthostatic Hypotension Market

DelveInsight's "Orthostatic Hypotension Market Insights, Epidemiology, and Market Forecast-2034" report delivers an in-depth understanding of the Orthostatic Hypotension, historical and forecasted epidemiology as well as the Orthostatic Hypotension therapeutics market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

The Orthostatic Hypotension market report provides current treatment practices, emerging drugs, Orthostatic Hypotension market share of the individual therapies, current and forecasted Orthostatic Hypotension market Size from 2020 to 2034 segmented by seven major markets. The Report also covers current Orthostatic Hypotension treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the Orthostatic Hypotension market.

Scope of the Orthostatic Hypotension Market

Study Period

2020 to 2034

Forecast Period

2024-2034

Geographies Covered 

  • The US, EU4 (Germany, France, Italy, and Spain) and UK, Japan

Orthostatic Hypotension Market

  • Total Market Size
  • Market Size by Therapies
  • Market Size by Class

Orthostatic Hypotensions Market Size

USD XX Million by 2034

Orthostatic Hypotension Companies

TSH Biopharm Corporation Limited, Lundbeck LLC, Chelsea Therapeutics, Theravance Biopharma, Juvantia Pharma Ltd, Theravance Biopharma, Shire, and others

Orthostatic Hypotension Epidemiology Segmentation

  • Total Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Total Diagnosed Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Gender-specific Diagnosed Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Age-specific Diagnosed Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Treated Cases of Orthostatic Hypotension in the 7MM

Orthostatic Hypotension Disease Undersatnding

The DelveInsight’s Orthostatic Hypotension market report gives a thorough understanding of the Orthostatic Hypotension by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis, and treatment.

Orthostatic Hypotension Overview

Orthostatic Hypotension is a clinical condition characterized by a significant drop in blood pressure when a person moves from a sitting or lying position to standing, typically defined as a decrease of at least 20 mmHg in systolic or 10 mmHg in diastolic blood pressure within three minutes of standing. It commonly results from impaired autonomic regulation, reduced blood volume, or medication effects, and is frequently observed in elderly individuals and patients with neurological disorders such as Parkinson’s disease, diabetes, or cardiovascular conditions. Clinically, OH presents with symptoms including dizziness, lightheadedness, blurred vision, weakness, and syncope, substantially increasing the risk of falls and negatively impacting quality of life. Management involves lifestyle modifications, addressing underlying causes, and pharmacological interventions aimed at stabilizing blood pressure and improving daily functioning.

Orthostatic Hypotension Diagnosis

Orthostatic Hypotension diagnosis is primarily based on measuring blood pressure and heart rate changes when a patient transitions from a supine or seated position to standing. A confirmed diagnosis typically involves a drop of at least 20 mmHg in systolic blood pressure or 10 mmHg in diastolic blood pressure within three minutes of standing. Clinical evaluation includes assessment of symptoms such as dizziness, lightheadedness, or syncope, along with a detailed medical history to identify contributing factors like medications, dehydration, or underlying neurological and cardiovascular disorders. Additional tests, including tilt-table testing, autonomic function tests, and laboratory evaluations, may be used to determine disease severity and identify underlying causes, supporting accurate diagnosis and treatment planning.

Orthostatic Hypotension Treatment

Orthostatic Hypotension treatment focuses on relieving symptoms, preventing falls, and addressing underlying causes. Initial management includes non-pharmacological measures such as increasing fluid and salt intake, gradual postural changes, compression garments, and reviewing medications that may worsen blood pressure drops. When symptoms persist, pharmacological therapies like midodrine and droxidopa are commonly used to improve vascular tone and raise standing blood pressure. Treatment is typically individualized based on disease severity, comorbid conditions, and patient tolerance, with the goal of improving daily functioning and quality of life.

It covers the details of conventional and current medical therapies available in the Orthostatic Hypotension market for the treatment of the condition. It also provides Orthostatic Hypotension treatment algorithms and guidelines in the United States, Europe, and Japan.

Orthostatic Hypotension Epidemiology 

The Orthostatic Hypotension epidemiology section provides insights about the historical and current Orthostatic Hypotension patient pool and forecasted trends for individual seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Orthostatic Hypotension market report also provides the diagnosed patient pool and their trends along with assumptions undertaken. 

Orthostatic Hypotension Epidemiology Key Findings

The disease epidemiology covered in the report provides historical as well as forecasted Orthostatic Hypotension epidemiology scenario in the 7MM covering the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan from 2020 to 2034.

Country Wise- Orthostatic Hypotension Epidemiology

The epidemiology segment also provides the Orthostatic Hypotension epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

Orthostatic Hypotension Epidemiology Segmentation

  • Total Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Total Diagnosed Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Gender-specific Diagnosed Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Age-specific Diagnosed Prevalent Cases of Orthostatic Hypotension in the 7MM
  • Treated Cases of Orthostatic Hypotension in the 7MM

Orthostatic Hypotension Drug Analysis

The drug chapter segment of the Orthostatic Hypotension report encloses the detailed analysis of Orthostatic Hypotension marketed drugs and late-stage (Phase-III and Phase-II) Orthostatic Hypotension pipeline drugs. It also helps to understand the Orthostatic Hypotension clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Orthostatic Hypotension Marketed Drugs

The report provides the details of the marketed products/off-label treatments available for Orthostatic Hypotension treatment.

Orthostatic Hypotension Emerging Drugs

The report provides the details of the emerging therapies under the late and mid-stage of development for Orthostatic Hypotension treatment.

Orthostatic Hypotension Market Outlook

The Orthostatic Hypotension market outlook of the report helps to build a detailed comprehension of the historic, current, and forecasted Orthostatic Hypotension market trends by analyzing the impact of current Orthostatic Hypotension therapies on the market, unmet needs, drivers and barriers, and demand for better technology.

This segment gives a thorough detail of Orthostatic Hypotension market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Orthostatic Hypotension market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to DelveInsight, the Orthostatic Hypotension market in 7MM is expected to witness a major change in the study period 2020-2034.

Key Findings

This section includes a glimpse of the Orthostatic Hypotension market in 7MM.

The United States Orthostatic Hypotension Market Outlook

This section provides the total Orthostatic Hypotension market size and market size by therapies in the United States.

EU-5 Countries Orthostatic Hypotension Market Outlook

The total Orthostatic Hypotension market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom is provided in this section.

Japan Orthostatic Hypotension Market Outlook

The total Orthostatic Hypotension market size and market size by therapies in Japan is also mentioned.

Orthostatic Hypotension Competitive Landscape

The orthostatic hypotension market is moderately competitive and dominated by established pharmaceutical companies and emerging innovators focused on expanding therapeutic options for this niche cardiovascular condition. Key market players include H. Lundbeck A/S (notably with droxidopa/Northera), Novartis AG, Pfizer Inc., Amneal Pharmaceuticals Inc., Mylan/Viatris Inc., and other multinational firms that offer core treatments such as midodrine, droxidopa, and fludrocortisone through broad distribution networks across hospitals, clinics, and retail pharmacies. Generics and alternative drug manufacturers (e.g., Sun Pharma, Cipla, Aurobindo) add pricing competition and improved accessibility, particularly in emerging markets.

Competitive strategies center on R&D innovation, product portfolio diversification, strategic collaborations, and digital health integration to enhance patient adherence and extend market reach. Additionally, growth opportunities are emerging from increased diagnosis rates, aging populations, and pipeline candidates including novel sympathomimetics and norepinephrine‑targeting agents intended to address unmet clinical needs.

Key Orthostatic Hypotension Companies

The Key Orthostatic Hypotension companies actively involved in the Orthostatic Hypotension treatment landscape include - 

  • Shire
  • TSH Biopharm Corporation Limited
  • Lundbeck LLC
  • Chelsea Therapeutics
  • Theravance Biopharma
  • Juvantia Pharma Ltd
  • Theravance Biopharma, and others

Orthostatic Hypotension Drugs Uptake

This section focuses on the rate of uptake of the potential Orthostatic Hypotension drugs recently launched in the Orthostatic Hypotension market or expected to get launched in the market during the study period 2020-2034. The analysis covers Orthostatic Hypotension market uptake by drugs; patient uptake by therapies; and sales of each drug.   

Orthostatic Hypotension Drugs Uptake helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs, and allow the comparison of the drugs on the basis of Orthostatic Hypotension market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Orthostatic Hypotension Clinical Trial Activities

The Orthostatic Hypotension pipeline report provides insights into Orthostatic Hypotension clinical trials within Phase II, and Phase III stage. It also analyses Orthostatic Hypotension companies involved in developing targeted therapeutics.

Orthostatic Hypotension Pipeline Development Activities

The Orthostatic Hypotension clinical trials analysis report covers the detailed information of collaborations, acquisition, and merger, licensing, patent details, and other information for Orthostatic Hypotension emerging therapies.

Orthostatic Hypotension Market Reimbursement Scenario

Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we take reimbursement into consideration to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

Latest KOL- Views on Orthostatic Hypotension Market Report

To keep up with current Orthostatic Hypotension market trends, we take KOLs and SMEs ' opinion working in the Orthostatic Hypotension domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies treatment patterns or Orthostatic Hypotension market trends. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the market and the unmet needs.

Orthostatic Hypotension Competitive Intelligence Analysis

We perform Competitive and Market Intelligence analysis of the Orthostatic Hypotension Market by using various Competitive Intelligence tools that include - SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies etc. The inclusion of the analysis entirely depends upon the data availability.

Scope of the Orthostatic Hypotension Market Report

  • The report covers the descriptive overview of Orthostatic Hypotension, explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
  • Comprehensive insight has been provided into the Orthostatic Hypotension epidemiology and treatment in the 7MM
  • Additionally, an all-inclusive account of both the current and emerging therapies for Orthostatic Hypotension is provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
  • A detailed review of the Orthostatic Hypotension market; historical and forecasted is included in the report, covering drug outreach in the 7MM
  • The report provides an edge while developing business strategies, by understanding trends shaping and driving the global Orthostatic Hypotension market

Orthostatic Hypotension Report Highlights

  • In the coming years, the Orthostatic Hypotension market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
  • The companies and academics are working to assess challenges and seek opportunities that could influence Orthostatic Hypotension R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition      
  • Several major Orthostatic Hypotension companies are developing novel therapies for better treatment outcome. The launch of emerging therapies will significantly impact the Orthostatic Hypotension market
  • A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for Orthostatic Hypotension
  • Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

Orthostatic Hypotension Market Report Insights

  • Orthostatic Hypotension Patient Population
  • Orthostatic Hypotension Therapeutic Approaches
  • Orthostatic Hypotension Pipeline Analysis
  • Orthostatic Hypotension Market Size and Trends
  • Orthostatic Hypotension Market Opportunities
  • Impact of Upcoming Orthostatic Hypotension Therapies

Orthostatic Hypotension Market Report Key Strengths

  • 10 Years Forecast
  • 7MM Coverage
  • Orthostatic Hypotension Epidemiology Segmentation
  • Key Cross Competition in the Orthostatic Hypotension Market
  • Highly Analyzed Orthostatic Hypotension Market
  • Orthostatic Hypotension Drugs Uptake

Orthostatic Hypotension Market Report Assessment

  • Current Orthostatic Hypotension Treatment Practices
  • Orthostatic Hypotension Unmet Needs
  • Orthostatic Hypotension Pipeline Product Profiles
  • Orthostatic Hypotension Market Attractiveness
  • Orthostatic Hypotension Market Drivers
  • Orthostatic Hypotension Market Barriers

Key Questions Answered In The Orthostatic Hypotension Market Report:

Orthostatic Hypotension Market Insights

  • What was the Orthostatic Hypotension drug class share (%) distribution in 2020 and how it would look like in 2034?
  • What would be the Orthostatic Hypotension total market size as well as market size by therapies across the 7MM during the forecast period (2020-2034)?
  • What are the key findings pertaining to the market across 7MM and which country will have the largest Orthostatic Hypotension market size during the forecast period (2020-2034)?
  • At what CAGR, the Orthostatic Hypotension market is expected to grow by 7MM during the forecast period (2020-2034)?
  • What would be the Orthostatic Hypotension market outlook across the 7MM during the forecast period (2020-2034)?
  • What would be the Orthostatic Hypotension market growth till 2034, and what will be the resultant market Size in the year 2034?
  • How would the unmet needs affect the market dynamics and subsequent analysis of the associated trends?

Orthostatic Hypotension Epidemiology Insights

  • What are the disease risk, burden, and regional/ethnic differences of the Orthostatic Hypotension?
  • What are the key factors driving the epidemiology trend for seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What is the historical Orthostatic Hypotension patient pool in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What would be the forecasted patient pool of Orthostatic Hypotension in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • Where will be the growth opportunities in the 7MM with respect to the patient population pertaining to Orthostatic Hypotension?
  • Out of all 7MM countries, which country would have the highest prevalent population of Orthostatic Hypotension during the forecast period (2020-2034)?
  • At what CAGR the patient population is expected to grow in 7MM during the forecast period (2020-2034)?

Current Orthostatic Hypotension Treatment Scenario, Marketed Drugs and Emerging Therapies

  • What are the current options for the Orthostatic Hypotension treatment in addition to the approved therapies?
  • What are the current treatment guidelines for the treatment of Orthostatic Hypotension in the USA, Europe, and Japan?
  • What are the Orthostatic Hypotension marketed drugs and their respective MOA, regulatory milestones, product development activities, advantages, disadvantages, safety and efficacy, etc.?
  • How many companies are developing therapies for the treatment of Orthostatic Hypotension?
  • How many therapies are in-development by each company for Orthostatic Hypotension treatment?
  • How many are emerging therapies in mid-stage, and late stage of development for Orthostatic Hypotension treatment?
  • What are the key collaborations (Industry - Industry, Industry - Academia), Mergers and acquisitions, licensing activities related to the Orthostatic Hypotension therapies?
  • What are the recent novel therapies, targets, mechanisms of action and technologies being developed to overcome the limitation of existing therapies?
  • What are the major ongoing Orthostatic Hypotension clinical studies and their status?
  • What are the current challenges faced in drug development?
  • What are the key designations that have been granted for the emerging therapies for Orthostatic Hypotension?
  • What are the global historical and forecasted market of Orthostatic Hypotension?

Reasons to Buy Orthostatic Hypotension Forecast Market Report

  • The report will help in developing business strategies by understanding trends shaping and driving the Orthostatic Hypotension market
  • To understand the future market competition in the Orthostatic Hypotension market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for Orthostatic Hypotension in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for Orthostatic Hypotension market
  • To understand the future market competition in the Orthostatic Hypotension market

Frequently Asked Questions

Orthostatic Hypotension is a condition where a sudden drop in blood pressure occurs upon standing up, leading to symptoms like dizziness, lightheadedness, and fainting.
Factors driving Orthostatic Hypotension market growth include increased recognition and diagnosis, aging populations leading to more cases, advancements in treatment options, and research focused on understanding the condition better.
Among the 7MM, the United States holds the largest Orthostatic Hypotension market share.
Influencing factors in the epidemiology of Orthostatic Hypotension across the seven major markets (7MM) include variations in diagnostic criteria, the prevalence of conditions contributing to Orthostatic Hypotension (like neurological disorders or cardiovascular conditions), and variations in healthcare access and reporting.
Treatment options for Orthostatic Hypotension often involve lifestyle modifications such as increasing fluid and salt intake, wearing compression stockings, and making slower movements when transitioning from sitting to standing. Medications like fludrocortisone, midodrine, or droxidopa may also be prescribed to manage symptoms.
Some of the leading pharma and biotech companies in the Orthostatic Hypotension market include TSH Biopharm Corporation Limited, Lundbeck LLC, Chelsea Therapeutics, Theravance Biopharma, Juvantia Pharma Ltd, Theravance Biopharma, Shire, among others.
The Orthostatic Hypotension market report covers in-depth insights into the evolving market dynamics, patient population, therapeutic approaches, pipeline therapies, and key companies working in the market.

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