Metastatic HER2-Positive Breast Cancer is one of the types of breast cancer in which breast cancer cells test show positive status for a protein receptor called human epidermal growth factor receptor 2. The normal function of this protein is to control how a healthy breast cell grows, divides, and repairs itself.
However, when there is a mutation in the gene that controls the HER2 protein, also known as erythroblastic oncogene B (ERBB2) gene, the body creates too many HER2 receptors, which results in uncontrollable breast cell growth and division. The most common signs of this indication are breast swelling, change in the shape of breast, skin irritation or dimpling, pain in the breast, redness or thickness of the breast skin.
Diagnosis of HER2-positive breast cancer is made by following recommended tests, such as the IHC test, the FISH test, the SPOT-Light HER2 CISH, and the Inform HER2 Dual ISH tests. These tests use antibodies or DNA to stain the cancer cells.
October is breast cancer awareness month; the main goal is to increase awareness regarding breast cancers. Many women die due to this disease! Let us aim to increase the recognition of breast cancer, symptoms, diagnosis and treatment.