Assessing the Growing Role & the Demand of Apps in Managing the Chronic Diseases

Neurology

Unveiling the Safety and Dosing Patterns of IPX...

IPX203 represents a groundbreaking advancement in Parkinson's disease (PD) treatment with its novel oral formulation of carbidopa/levodopa (CD/LD) extended-release capsules. Unlike existing options...

Apr 22, 2024

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A New Dawn: Frexalimab’s Quest to Redefine Multiple Sclerosis Therapy

Frexalimab (SAR441344) is a novel anti-CD40L antibody in development, designed to inhibit the CD40/CD40L pathway, a crucial element in activating both adaptive and innate immune responses. Its distinctive mode of action targets neuroinflammation in multiple sclerosis, offering potential benefits for both acute and...

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AXS-07 Shines at AAN 2024: A New Era in Migraine Treatment

AXS-07, a cutting-edge oral solution, blends MoSEIC meloxicam and rizatriptan, offering rapid absorption. It ingeniously inhibits CGRP release, counteracting vasodilation, and curbing neuroinflammation and pain transmission for enhanced relief. AXS-07 demonstrates superior efficacy in swiftly alleviating migrai...

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Target Engagement of UB-312 in Parkinson’s Disease Patients: Insights from CSF Analysis

UB-312 represents a promising avenue in Parkinson's disease (PD) treatment by focusing on pathological forms of alpha-synuclein (aSyn), a key protein associated with the progression of synucleinopathies. Unlike conventional approaches, UB-312 aims to elicit antibodies that specifically recognize and neutralize the...

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More Views & Analysis

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Charting Progress: Ozanimod’s Influence on Brain Dynamics in RMS

ZEPOSIA (ozanimod), a breakthrough approved in March 2020 for Relapsing Forms of Multiple Sclerosis (RMS), utilizes oral sphingosine 1-phosphate (S1P) receptor modulation to impede lymphocyte migration, offering a novel approach in multiple sclerosis treatment. ENLIGHTEN (NCT04140305) explores ozanimod's impact...

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Breakthroughs in Parkinson’s Management: Key Findings from Neuroderm’s ND0612 Studies

NeuroDerm's ND0612 introduces a pioneering approach to Parkinson's disease management with its self-administered continuous subcutaneous infusion of levodopa/carbidopa. Unlike traditional oral formulations, ND0612 bypasses the gastrointestinal tract, offering increased bioavailability and potentially more reliable...

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Enhancing Patient Care: Transitioning from Eculizumab to Ravulizumab in gMG Management

Eculizumab (SOLIRIS) and ravulizumab (ULTOMIRIS) are two approved therapies for the treatment for adult patients with generalized Myasthenia Gravis (gMG) who are anti-acetylcholine receptor antibody-positive. The findings presented by Alexion, AstraZeneca Rare Disease unveil a remarkable decline in Myasthenia G...

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Revolutionizing gMG Treatment: Efgartigimod’s Triumph in Curtailing Oral Corticosteroid Dependence

Efgartigimod (VYVGART/VYVGART Hytrulo) is a prescription medicine for the treatment of gMG in adults who are positive for antibodies directed toward a protein called acetylcholine receptor (anti-AChR antibody positive). It is designed as a first-in-class investigational antibody fragment to target the neonatal Fc ...

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Advancing Parkinson’s Disease Treatment: P2B001 Offers Promising Safety Profile in Early PD Patients

P2B001, a novel once-daily combination therapy, uniquely merges extended-release pramipexole and rasagiline in low doses, targeting Parkinson's Disease (PD) with enhanced efficacy and minimized side effects. The analysis presented by Pharma Two B highlighted P2B001's impressive safety and tolerability profile c...

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Unveiling the Promising Long-Term Potential of Subcutaneous Efgartigimod PH20 in Managing gMG

Efgartigimod PH20 is a combination subcutaneous (SC) infusion that contains efgartigimod alfa and hyaluronidase which may be used to improve muscle weakness in adults with generalized myasthenia gravis (gMG) who are anti-AChR antibody positive. The interim results presented by Argenx highlighted notable efficac...

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With worldwide dissemination and now over 9 million cases and nearly 500,000 deaths recorded, the ef.....

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Myocardial infarction (MI), colloquially known as “heart attack” is caused by decreased or compl.....

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A rare neurological disorder characterized by progressive weakness and impaired sensory function in .....

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A chronic pain condition, Complex Regional Pain Syndrome (CRPS) often affects one limb and is believ.....

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Immunity is a major concern in the present times, and consumers have increased their focus on boosti.....

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Lyme disease is a vector-borne infectious disease that spreads primarily by the bite of a tick (also.....

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