DelveInsight

Oct 06, 2017

C-X-C chemokine receptors (CXCR) is a family of G protein-coupled receptors that comprises of a large subfamily of the rhodopsin superfamily of 7-transmembrane domain receptors. Two types of chemokine receptors have been identified including monogamous chemokine receptors (bind to only one specific chemokine) and pr...

Sep 28, 2017

Another flop for Alzeimer’s as Late Stage drug of AxovantSciences fails in trial Axovant Sciences has reported the failure of their late-stage trial involving the testing of its pill Intepirdinecould not suppress Alzheimer's symptoms in participants of the trail. The news had plunged the Wall Street into another wav...

Sep 22, 2017

The enzyme, isocitrate dehydrogenase (IDH) catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate and CO2. It is found in the cytosol, mitochondrial matrix, and peroxisomes. IDH is responsible for cellular respiration in the TCA cycle. Isocitrate dehydrogenase exists in three isoforms i...

Sep 20, 2017

Chinese pharma company Shanghai Fosun to acquire 74% stake in Indian company Gland Pharma for $1.09 billion In July last year Chinese company Shanghai Fosun Pharmaceutical announced to acquire 74% per cent stake in Gland Pharma (Hyderabad-based Company) for not more than USD 1.09 billion. Initially the deal was set...

Sep 18, 2017

Oral Mucositis is a commonly occurring, most debilitating complication of cancer chemotherapy and radiotherapy. It can be characterized by inflammation and ulceration in the oral cavity caused by the chemotherapeutic drugs and radiotherapy used in cancer treatment. Potential complications of oral mucositis include p...

Sep 15, 2017

Bayer and Berkeley Lights embark on a project to automate drug discovery Pharmaceutical giant Bayer and Berkeley Lights have announced their collaboration to conduct a strategic project on a discovery platform aimed to automate antibody discovery and development of cell lines. Bayer and Berkeley Lights’ platform- Be...

Aug 09, 2017

Genetically engineered salmon has reached the dinner table, as AquaBounty Technologies, a Massachusetts company has successfully developed and commercialized a genetic variant of salmon fish, Salmo salar. The company announced that it has sold some 4.5 tonnes of its hotly debated product to customers in Canada. This...

Jul 25, 2017

Samsung and Merck launch Remicade biosim at 35% discount After the first biosimilar of Johnson & Johnson’s big-selling immunology drug Remicade hit the market last year at a modest discount, another has come along with a much deeper pricing slash. Samsung and marketing partner Merck & Co. Monday launched the...

Jul 18, 2017

Takeda scores blockbuster Velcade patent reprieve till 2022 In a major lift for Takeda and its aging multiple myeloma blockbuster Velcade, a U.S. appeals court overturned a ruling that invalidated a key patent, granting new exclusivity that should translate to significant sales over time. Takeda will have exclusive ...

Jul 12, 2017

Obstetrician and gynaecologist Brenda Fitzgerald will direct the US Centers for Disease Control and Prevention (CDC), which was announced on 7th July. Dr. Brenda Fitzgerald has led the Georgia Department of Public Health since 2011, and has championed early-intervention programmes to improve maternal health and coun...