Systemic Lupus Erythematosus

Jul 24, 2026

Summary Lupus nephritis (LN) is a severe, often silent complication of systemic lupus erythematosus (SLE) that progressively damages kidneys without obvious early symptoms, leading to delayed diagnosis and irreversible harm. Globally, ~1.4 million people live with LN; in the US, cases are projected to reach ...

Jul 22, 2026

Summary Systemic lupus erythematosus is a highly unpredictable autoimmune disease characterized by fluctuating flares affecting multiple organs, impacting ~5 million people globally and ~513,000 diagnosed cases in the US (2025), with numbers expected to rise through 2036. Diagnosis is complex and lengthy, of...

Jul 22, 2026

Summary SLE is a chronic autoimmune disease affecting multiple organs, with ~936K diagnosed cases across the 7MM in 2025 and expected growth by 2036. BENLYSTA (belimumab, GSK) remains the cornerstone biologic, targeting BLyS to reduce autoreactive B cells; it expanded into lupus nephritis, pediatrics, and mu...

Jul 21, 2026

Summary Systemic lupus erythematosus, once considered highly unpredictable and difficult to treat, is undergoing a major therapeutic transformation driven by biologics, small molecules, and cell-based therapies. The SLE market is valued at around USD 3 billion in 2025 across the 7MM and is projected to grow ...

May 29, 2026

Systemic lupus erythematosus (SLE) is a chronic autoimmune condition that can affect multiple parts of the body. In 2025, it was estimated that around 512,000 individuals in the United States were living with SLE, as per DelveInsight analysis, with new treatments for SLE urgently needed as 40% of treated SLE patien...

Dec 23, 2025

Novo Nordisk Submits CagriSema for FDA Review as a Once-weekly GLP-1–amylin Combination Therapy for Weight Management Novo Nordisk has officially filed a New Drug Application (NDA) with the U.S. FDA for CagriSema, a once-weekly subcutaneous injection intended for chronic weight management. CagriSema represents a...

Dec 22, 2025

Chimeric Antigen Receptor T-cell (CAR-T) therapy has established itself as one of the most disruptive innovations in modern medicine. Since the first approval in 2017, CAR-T therapies have transformed outcomes in hematologic malignancies, achieving deep, durable remissions in patient populations previously resistan...

Oct 27, 2025

As the lupus treatment landscape undergoes major changes, Roche is entering the US lupus nephritis market with a fresh FDA approval for its long-standing blood cancer drug, GAZYVA. On October 20, 2025, Roche’s Genentech division announced that the FDA had approved GAZYVA (obinutuzumab) for use in adults with active...

Jun 10, 2025

Imagine a world where treatment options are as precise as a scalpel and as adaptable as a chameleon. Bispecific antibodies are paving the way for this future, bringing revolutionary advancements in oncology and various therapeutic fields. By harnessing the power of these dual-targeting agents, researchers are unloc...

Apr 04, 2023

HUTCHMED Completes Rolling Submission of NDA to FDA for Fruquintinib HUTCHMED (China) Limited announced the completion of the rolling submission of a New Drug Application ("NDA") to the United States Food and Drug Administration ("FDA") for fruquintinib, its highly selective and potent oral inhibitor of VEGFR-1,...