Type 1 Diabetes (T1D) arises from the autoimmune destruction of insulin-producing islet cells in the pancreas. This destruction results in a complete loss of insulin production, leading to significant impairment in blood glucose control. Without insulin, the body cannot properly process nutrients, causing persistently high blood glucose levels.
High blood glucose can precipitate diabetic ketoacidosis and, over time, lead to severe complications such as kidney disease/failure, eye disease (including vision loss), heart disease, stroke, nerve damage, and even death. Managing T1D is further complicated by the limitations and complexities of current insulin delivery sy...