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Cholera vaccine delivered; Rice-inspired breakthroughs; International partnerships

Cholera vaccine delivered through a cup of rice water Vaccinations against prevalent pathogens could be ingested as oral or inhaled as nasal vaccines, this is due to the development of non-invasive vaccines, which target the mucous membranes. These could help fight a plethora of infectious diseases such as cholera,...

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Cancer
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National health authorities, U.K.'s NICE determines Gilead's cancer cell therapy exorbitant The National Institute for Health and Care Excellence (NICE) found Gilead's cancer cell therapy, Yescarta to be clinically efficacious for treating a type of lymphoma, but no ample evidence is present to estimate the benefit...

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acute myeloid leukemia
Predicting risk of Acute Myeloid Leukemia (AML) in healthy individuals

The occurrence of acute myeloid leukemia (AML) keeps on increasing with age and mortality surpasses 90% if diagnosed after age of 65. Most cases emerge with no perceivable early side effects and patients generally give the intense intricacies of bone marrow failure. The beginning of such oinitial acute myeloid leuke...

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Acute lymphoblastic leukemia
New method for classification of CNS tumors

Precise pathological diagnosis is crucial for proper management of patients suffering from cancer. There are approximately 100 known tumor types of the central nervous system. Due to Large number of tumor type standardization of the diagnostic process is very challenging. Researchers are now working on a completely ...

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Connection between Immune cells in the brain and Alzheimer’s disease The spreading of pathology within and between brain areas is a hallmark of neurodegenerative disorders. In patients with Alzheimer’s disease, deposition of amyloid-β is accompanied by activation of the innate immune system and involves the inflamma...

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Ketamine to work in mice

Gender matters for Party drug Ketamine to work its anti-depressant activity in mice Experiments involving the popular party drug ketamine, a psychoactive recreational drug used to uplift mood of the user, in mice has deepened the mystery of how the dug affects the brain further. Results of a study conducted at the U...

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‘Killer’ Mosquito to be released in 20 US states to fight mosquitoes

'Killer' Mosquito to be released in 20 US states to fight disease-causing mosquitoes The US Environmental Protection Agency (EPA) has approved the use of a common bacterium to kill wild mosquitoes that transmit viruses such as dengue, yellow fever and Zika. The biotechnology start-up MosquitoMate means to release th...

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Personalized Medicine
Georgia physician to lead US public-health agency

Obstetrician and gynaecologist Brenda Fitzgerald will direct the US Centers for Disease Control and Prevention (CDC), which was announced on 7th July. Dr. Brenda Fitzgerald has led the Georgia Department of Public Health since 2011, and has championed early-intervention programmes to improve maternal health and coun...

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China cracks down on fake peer reviews

The Chinese government is going on the offensive against scientists who dupe journals by creating fraudulent reviews of submitted papers. A coalition of agencies led by the science ministry announced on 14 June that the government would suspend the grants of researchers involved in such fraud, which surfaced earlier...

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The Snippet: Targeting metabolism in Renal Cell Carcinoma

Loss of VHL and elevated expression of HIF transcription factors leads to reprogramming of tumour cell metabolism, enabling renal cell carcinoma (RCC) cells to use carbons from glutamine-derived aspartate to drive pyrimidine biosynthesis. Now, researchers show that inhibition of glutamine availability decreases aspa...

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