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South Korea’s scientists seek change amid political chaos

When South Korea’s Constitutional Court removed scandal-ridden President Park Geun-Hye from office on 10 March, citizens rejoiced in the streets — and many scientists breathed a sigh of relief. Her downfall has inspired a public appetite for broad governmental reforms, including changes in how the country supports s...

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New biomarkers for screening in Pancreatic Cancer

Data from three cohorts of patients with early stage pancreatic ductal adenocarcinoma (PDAC) indicate that a two-protein biomarker panel, consisting of plasma tissue factor pathway inhibitor (TFPI) and tenascin-C (TNC-FN-III-C), as measured in plasma samples using an ELISA improves the prognostic value of CA 19-9. T...

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The Snippet: Delay in hiring science advisers intensifies Brexit worries

Two government departments charged with managing the United Kingdom’s departure from the European Union have not yet appointed chief scientific advisers (CSAs) — and might not do so. That is starting to concern science-policy experts, who worry that scientists won’t be at the table when government makes key decision...

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Clinical trials need to assess drug efficacy before trials

On 17 January 2016, a healthy man was declared brain-dead after receiving an experimental drug in a first-in-human trial in France. Four of five other subjects receiving the same dose have serious, ongoing neurological complications. Investigations into the trial described many troubling safety practices, such as st...

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Pulling the apoptotic trigger for necrosis

Apoptosis and necrosis are considered to be distinct modes of cell death; however, apoptosis can progress to secondary necrosis if apoptotic cells are not efficiently removed by phagocytic cells. Secondary necrosis was thought to be unregulated and to occur through passive cell swelling. However, research shows that...

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