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Oxcia’s OXC-201 is a small molecule inhibitor of OGG1, a potential breakthrough for treating IPF (idiopathic pulmonary fibrosis), other fibrotic conditions, and inflammatory diseases while providing a unique mechanism of action that affects multiple signaling pathways and pathological processes associated with IPF, potentially preventing further lung damage.
OXC-201 in IPF
Oxcia’s OXC-201 is a small molecule inhibitor of OGG1, a potential breakthrough for treating IPF (idiopathic pulmonary fibrosis), other fibrotic conditions, and inflammatory diseases while providing a unique mechanism of action that affects multiple signaling pathways and pathological processes associated with IPF, potentially preventing further lung damage.
Clinical Trials
Treprostinil palmitil data presented for PH-ILD
Current treatment for PH-ILD involves the use of drugs like bosentan (an endothelin receptor antagonist), sildenafil (a phosphodiesterase-5 inhibitor), and epoprostenol (a prostacyclin analog) to relieve pulmonary vascular constriction and enhance lung blood flow, ultimately reducing elevated pulmonary artery pressure.
Clinical Trials
Efzofitimod's Victory
aTyr, working to develop a new class of drugs based on the extracellular biology of tRNA synthetase, Efzofitimod, presented a post-hoc analysis of the Phase Ib/IIa study in pulmonary sarcoidosis at the European Respiratory Society (ERS) at International conference taking place in Milan, Italy from September 9 to 13, 2023.
Clinical Trials
Brensocatib’s Breakthrough: A Ray of Hope for Cystic Fibrosis and Beyond at ERS International Congress 2023
Insmed Inc.’s creation, Brensocatib, a small oral molecule acting as a reversible inhibitor of dipeptidyl peptidase 1 (DPP1), holds substantial promise for patients with both CF and NCFBE. DPP1 is an enzyme accountable for triggering neutrophil serine proteases (NSPs) in neutrophils, pivotal white blood cells central to infection defense and inflammation regulation.
Clinical Trials
ERS 2023 Reveals Efzofitimod Data
In a monumental stride toward combating Systemic Sclerosis-Interstitial Lung Disease (SSC-ILD), aTyr Pharma, Inc. unveiled the data related to its first-in-class drug, Efzofitimod, at the European Respiratory Society (ERS) International Congress 2023.
Clinical Trials
Arrowhead’s RNAi Candidate at ERS 2023
As per DelveInsight’s analysis, the estimated market size for asthma in 2022 stood at approximately USD 18,460 million. However, with the introduction of new emerging drugs, the market is expected to experience substantial growth.
Clinical Trials

Gout is a chronic disease caused by the deposition of monosodium urate (MSU) crystals in joints. It typically presents as an acute, self-limiting inflammatory monoarthritis that affects the joints of the lower limb. Various symptoms of Gout include intense joint pain, joint swelling, stiffness, tenderness, even to light touch, such as from a bedsheet, heat in the affected area, and joint redness.

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