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Novel biomarkers in Rheumatic and Musculoskeletal Diseases

Novel biomarkers: Rheumatic & Musculoskeletal Diseases

Biomarker studies have added value to real-world data collections in inflammatory arthritis, and some of them have the potential to be used in routine clinical practice.

Digital/Remote Health Applications for Self-management in Patients With Rheumatic Diseases
Eli Lilly to present baricitinib’s results for juvenile idiopathic arthritis from its Phase III safety and efficacy study at EULAR 2022.
EULAR 2022: A glimpse of Abbvie’s Oral Presentation on Upadacitinib for treatment of Nonradiographic Axial Spondyloarthritis.

Our Recent Articles

Title

Musculoskeletal Imaging in Rheumatology

Summary

There are about 200 different types of rheumatic and musculoskeletal diseases (RMDs) that affect both children as well as adults. The group of diseases is usually caused owing to a compromised immune system or by inflammation, infections, and gradual deterioration caused in the joints, muscles, and bones.

Article Type

Research And Development

Title

ABX464: A Potential Candidate With a Novel Mechanism of Action for the Treatment of Rheumatoid Arthritis

Summary

ABX464 met the primary endpoint revealing a favorable safety and tolerability profile in the Phase IIa clinical trial, displaying its potential and effectiveness for treating patients with moderate to severe RA and inadequate response to MTX and/or anti-TNFα therapeutics.

Article Type

Poster abstract

Title

Bimekizumab to Benefit Psoriatic Arthritis Patients According to the Phase III Clinical Trial Results

Summary

Bimekizumab met the primary and secondary endpoints with an acceptable safety profile in the Phase III clinical trial. It displayed its potential effectiveness for treating patients with active PsA and prior inadequate tumor necrosis factor inhibitor (TNFi) response.

Article Type

Title

Deucravacitinib: A Ray of Hope after a decade of wait! BMS plans to progress its potential game changer oral TYK2 inhibitor into late stage clinical development

Summary

BMS presented positive results of its 48-week Phase II study at EULAR 2022 indicating that deucravacitinib met both primary and secondary endpoints and was safe, well tolerated and effective for people with lupus. Study participants who received the oral drug saw greater improvements in several measures of disease activity, including overall activity and organ-specific activity, compared to the placebo group.

Article Type

Clinical Trials

Title

Dual inhibition of IL-17A & IL-17F with bimekizumab may be a promising treatment option for AS, suggests BE MOBILE 2 trial.

Summary

Bimekizumab met the primary and secondary endpoints with an acceptable safety profile in Phase III clinical trial, displaying its potential effectiveness for the treatment of patients with active AS and an inadequate response or intolerance to two nonsteroidal anti-inflammatory drugs and prior exposure to no more than one tumor necrosis factor (TNF) inhibitor.

Article Type

Clinical Trials

Title

Upadacitinib shows promising results for nr-axSpA treatment of patients with inadequate response to biologic disease-modifying antirheumatic drugs.

Summary

Upadacitinib met the primary and secondary endpoints with an acceptable safety profile in the Phase III clinical trial, displaying its potential effectiveness for the treatment of nr-axSpA in patients with inadequate response to biologic disease-modifying antirheumatic drugs.

Article Type

Clinical Trials

Case Studies

Partner Identification

Partner Identification

Partners Identification for client's early-stage oncology-based clinical product for late-stage clinical development & commercialization.

Pipeline Assessment

Pipeline Assessment

Assessment of pipeline activities around the client's area of interest to support strategic decisions.

Epidemiology Assessment

Epidemiology Assessment

In-depth assessment to understand the epidemiological scenario of Cutaneous Squamous Cell Carcinoma

Market Assessment

Market Assessment

Evaluation of the oncological market potential of the asset gained through the acquisition and collaborations

Product Assessment

Product Assessment

Performance evaluation of new assets based on the Lead and Lag KPI

Newsletter and Whitepapers

Gout newsletter

Gout Market is Anticipated to Expand Due to Active as well as Emerging Pipeline Therapies

Gout is a chronic disease caused by the deposition of monosodium urate (MSU) crystals in joints. It typically presents as an acute, self-limiting inflammatory monoarthritis that affects the joints of the lower limb. Various symptoms of Gout include intense joint pain, joint swelling, stiffness, tenderness, even to light touch, such as from a bedsheet, heat in the affected area, and joint redness.

Latest Reports

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