generalized myasthenia gravis treatment

Aug 29, 2025

Myasthenia gravis is a rare autoimmune neuromuscular disorder marked by fluctuating muscle weakness due to impaired communication between nerves and muscles. Most cases involve autoantibodies against Acetylcholine Receptors (AChRs), reducing their numbers, blocking function, or disrupting alignment, leading to dimi...

May 16, 2025

The FDA has approved Johnson & Johnson’s anti-FcRn antibody, nipocalimab, for the treatment of generalized myasthenia gravis (gMG). This myasthenia gravis drug will be marketed under the name IMAAVY. Although J&J isn’t the first to receive FDA approval for an FcRn-blocking antibody in this indication, the c...

May 06, 2024

Autoimmune disorders, a group of conditions where the immune system mistakenly attacks healthy cells, affect millions worldwide, often leading to debilitating symptoms and reduced quality of life. Traditional treatments for autoimmune disorders have primarily focused on suppressing the immune system, which can leav...

Aug 01, 2022

Though a rare disease, generalized myasthenia gravis (gMG) still affects around 60,000 people in the US and another 100,000 in EU-5 and Japan. As per our analysis, the total diagnosed prevalent cases of gMG were approx 116K in the 7MM in 2021. These numbers are further estimated to increase by 2032. Moreover, t...