Fabry Disease is an inherited lysosomal storage disease caused by a nonfunctional or partially functional enzyme called alpha galactosidase A (α-Gal A). Decreased activity of α-Gal A in lysosomes results in the accumulation of enzyme substrates (Gb3 and lyso-Gb3) which cause cellular damage in tissues throughout the body. Currently, there is no permanent cure for Fabry Disease. But, recent developments in the Fabry Disease treatment scenario are leading to a symptomatic cure, relieving the condition. Fabry Disease symptoms include pain that spreads through the body (called a Fabry crisis), gastrointestinal complications, headaches, impaired sweating, vertigo, and hear...
