Pfizer tightens DMD patient criteria after serious adverse events in phase 3 gene therapy trial
Pfizer is tightening up the criteria for Duchenne muscular dystrophy patients to partake in phase 3 clinical trials of its experimental gene therapy after three severe events were cropping up in ongoing studies.
The New York-based Big Pharma declared the news with the DMD community in a letter for the Parent Project Muscular Dystrophy patient advocacy group. Pfizer said three cases of muscle weakness, including inflammation of the heart tissue called myocarditis, were observed in patients after fordadistrogene movaparvovec treatment. The adverse events were attr...