Congenital Adrenal Hyperplasia (CAH) is a group of inherited genetic disorders that affect adrenal gland function, most commonly caused by a deficiency in the enzyme 21-hydroxylase. This enzyme deficiency disrupts the production of cortisol and often aldosterone, leading to hormonal imbalances and excess androgen production. Per DelveInsight’s estimates, as of 2024, the total number of diagnosed prevalent cases of CAH across the 7MM [the United States, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan] reached ~69K cases. The United States stands out as the largest market with accounting for ~50% of these cases.
CAH is more than a rare di...
