Diabetes

A New Dawn for CRISPR, Intellia Edits Cells Inside the Body Intellia Therapeutics, along with its partner Regeneron Pharmaceuticals, recently announced its successful attempt in editing the cells inside the body leveraging the CRISPR technique. The world’s first-ever trial that has their DNA edited through an in...

Diabetes is a condition in which the blood glucose (blood sugar) level is abnormally high. Glucose, which is obtained from the food consumed, is the primary source of energy in the body. However, the excess glucose level in the blood can cause health issues over time and can lead to vision disorders like Diabetic R...

FDA Validates Use of Amgen’s KRAS Inhibitor in Lung Cancer  In a pathbreaking move, Amgen has gone ahead to emerge as a trailblazer in the undruggable lung cancer space with the approval of its KRAS inhibitor, Lumakras. For eons, the researchers grappled to come up with an effective and potential drug to ta...

Neuropathy is the most usual complication that occurs due to diabetes, affecting up to about 50% of the patients. Painful diabetic neuropathy tends to take place in ~25% of the patients suffering from diabetes mellitus. These patients get treated in office settings, and it affects their quality of life. It also occ...

Diabetes today is a significant health issue for many countries worldwide. As per the WHO, “the number of people with diabetes rose from 108 million in 1980 to 422 million in 2014. The increasing prevalence has been observed to rise more rapidly in low- and middle-income countries than in high-income countries”. Si...

FDA rejects BioMarin's gene therapy and Gilead's filgotinib over concerns The FDA refused to approve BioMarin's hemophilia A gene therapy valoctocogene roxaparvovec. The U.S. regulator that had earlier told there was no requirement of an AdComm for the drug, aka, valrox, has issued a complete response (CRL) lett...

The global healthcare system over the past few decades has transformed exponentially. Today we are living twice as long as our ancestors have lived before. Infrastructure development, technological advancements (such as accurate diagnosis and lesser medical errors), public-private partnerships in healthcare, availa...

50 million people globally have dementia, and out of all the dementia cases, Alzheimer’s Disease accounts for about 60–70% of cases, says the WHO. Alzheimer's Disease is a neurodegenerative disease, a common cause of dementia that affects behavior, memory, and thinking abilities of an individual. Mostly the symptom...

Uveitis is an ocular inflammation of the uveal tract, the middle layer of the eyeball. The uveal layer is responsible for nourishing the eye, and if damaged, leads to progressive and irreversible damage. Uveitis generally starts from the damage in the uveal layer; however, the disease is not at all confined to the ...

As per WHO, “Cancer is the second leading cause of death globally and is responsible for an estimated 9.6 million deaths in 2018. Globally, about 1 in 6 deaths is due to cancer”. The patients whose lives are afflicted with similar types of cancers have long been administered a similar type of treatment regimen b...