Affecting roughly 1–2 people per 100,000 each year, essential thrombocythemia is often silent, discovered during routine blood tests, yet it can quietly impact quality of life. The total number of diagnosed cases of essential thrombocythemia in the US was approximately 167,000 cases in 2024. In the United States, the highest number of age-specific cases was recorded for individuals aged 60 years and older, i.e., ~109,000 cases in 2024. Followed by the age group of 40-60 yrs and <40yrs.
While the exact cause is linked to mutations such as JAK2, CALR, or MPL, modern treatments, ranging from low-dose aspirin to targeted therapies, help manage risks and enable indiv...
