How Robots Are Introducing A New Dimension To Healthcare Service Delivery

Pharmaceutical

The Unmet Needs in Glaucoma Treatment: Bridging...

Glaucoma, often dubbed as the “silent thief of sight,” poses a significant challenge in the domain of ophthalmology. Glaucoma treatment has made significant strides, yet several unmet needs persist...

Apr 12, 2024

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DOC1021 – Unveiling Hope: Diakonos Oncology’s Breakthrough in Glioblastoma Treatment: AACR 2024

Glioblastoma or Glioblastoma Multiforme (GBM) represents the most common primary tumor of the central nervous system (CNS). Despite advancements in diagnostic approaches and the development of new therapies, the prognosis for glioblastoma patients remains notably poor, with limited improvement observed. At AACR ...

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Phase I/II trial of copanlisib in combination with nivolumab for microsatellite stable (MSS) colorectal cancer (CRC)

The findings presented at the 2024 AACR conference revealed that among patients diagnosed with PIK3Ca-mutated MSS mCRC (n = 22), three patients attained a partial response (PR). Additionally, one more patient with PIK3Ca-mutated mCRC maintained stable disease (SD). The study successfully achieved its primary endpoi...

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OBX-115 – TIL Cell Therapy Advancements for ICI-Resistant Advanced Melanoma: AACR 2024

Melanoma, a type of skin cancer, poses a significant health concern globally. Advanced and metastatic stages of melanoma present particularly formidable challenges, often necessitating innovative treatment approaches to address their aggressive nature and high mortality rates. Patients with ICI-resistant metasta...

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Personalized vaccine TG4050 induces polyepitopic immune responses against private neoantigens in resected HPV-negative head and neck cancers

TG4050 is a neoantigenic cancer vaccine derived from Transgene's myvac platform and leverages NEC's Artificial Intelligence (AI) technologies to identify and predict the most potent neoantigens for immunogenicity. According to the data presented at the AACR 2024 conference, at a median follow-up duration of 18.6 mo...

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ALX Oncology’s Evorpacept Combo Shows Strong Response in Relapsed B-NHL Patients: AACR 2024

The presentation by ALX Oncology at the AACR Annual Meeting 2024 provided promising insights into the efficacy and safety of their investigational drug, evorpacept, in combination with standard rituximab and lenalidomide for patients with relapsed or refractory B cell non-Hodgkin lymphoma (R/R B-NHL). The Phase ...

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Safety and preliminary efficacy of AZD1390 + radiation therapy (RT) for glioblastoma (GBM)

As per the data presented at the AACR 2024 conference, of the 21 patients who received AZD1390 in conjunction with radiation therapy at manageable doses, the median overall survival (OS) stood at 12.7 months. In arm A, comprising 75 patients with recurrent glioblastoma, the combination therapy of AZD1390 and IMR...

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Alectinib in children and adolescents with solid or CNS tumors harboring ALK-fusions: Data from the iMATRIX Alectinib Phase I/II open-label, multi-center study

According to the data presented at the AACR 2024 conference, as of the data cutoff date of June 12, 2023, a total of 8 patients at a median age of 11 years diagnosed with inflammatory myofibroblastic tumor (n=2), high-grade glioma (n=3), renal cell carcinoma (n=2), and anaplastic large cell lymphoma (n=1, protocol ...

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First-in-human dose-expansion study of NBF-006, a novel investigational siRNA targeting GSTP, in patients with KRAS-mutated non-small cell lung cancer

Glutathione S‑transferase Pi (GSTP) has a role in detoxification and anti‑oxidative damage response. Additionally, GSTP has a chaperone function that regulates key oncogenic pathways such as the KRAS and JNK. Since redundant pathways could compensate for the inhibition of a single kinase, targeting multiple pathway...

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Medical Odyssey: Solving the Dynamic Puzzle of Global Tourism Market

The Medical Tourism market has emerged as a dynamic sector in recent years, experiencing significant evolution driven by a myriad of factors. Traditionally, Medical Tourism referred to the practice of traveling abroad for medical treatment, often sought due to cost considerations, access to advanced technologies, o...

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Acute ischemic stroke (AIS) is a medical emergency caused by decreased blood flow to the brain, whic.....

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Digital therapies are evidence-based clinical approaches powered by software applications designed t.....

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Gout is a chronic disease caused by the deposition of monosodium urate (MSU) crystals in joints. It .....

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It was assumed initially that Alzheimer’s Disease was a rare condition, but now it is considered t.....

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In the past few years, online buying has become the easiest way to purchase products and services. T.....

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Anorexia Nervosa (AN) is a psychological condition that is characterized by an abnormally low weight.....

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