Pulmonary hypertension associated with interstitial lung disease (PH-ILD) is a serious, progressive complication characterized by increased Pulmonary Vascular Resistance (PVR) and disrupted gas exchange. This rise in PVR places extra stress on the right side of the heart, eventually leading to right heart dysfunction and failure if untreated. PH-ILD develops in patients with various fibrosing or inflammatory lung diseases that gradually scar lung tissue and damage the pulmonary vasculature.
The main underlying causes include Idiopathic Pulmonary Fibrosis (IPF), which is the most common and best-studied driver of PH-ILD, along with Nonspecific Interstitial Pneumonia...
