The acute respiratory distress syndrome (ARDS) prevalence is increasing every year; it is estimated that in the United States alone, about 190K Americans are diagnosed with ARDS each year. Prior to the COVID-19 global pandemic, more than 700K individuals in the US and 2 million cases globally developed ARDS from trauma, sepsis, bacterial, and viral infections, with a cumulative mortality of 40%. The COVID-19 pandemic has highlighted several severe unmet needs in the ARDS domain these include starting with the lack of effective FDA-approved pharmacotherapies, as neither SARS-CoV-2 vaccinations nor anti-SARS-CoV-2 vaccines address the unregulated inflammation that promo...
